Use of Optical Coherence Tomography to Assess Properties of Cutaneous Defects Following Radiofrequency Microneedling and Laser Treatment.

Objectives: To characterize the properties of cutaneous defects created by energy-based devices using optical coherence tomography.

Materials And Methods: Radiofrequency (RF) microneedling and non-ablative fractional laser (NAFL) treatment were performed in vivo with various parameters. Following treatment, optical coherence tomography (OCT) was used to image and measure cutaneous defects at multiple time points over a 24 h period.

Intradermal Delivery of Calcium Hydroxylapatite With Fractionated Ablation.

Objectives: The absorption of biostimulatory particulate matter following its application to fractional skin defects remains poorly understood, and even less is known about its in vivo impact in terms of tissue integration. The objectives of this study are twofold: (1) to evaluate the potential of calcium hydroxylapatite (CaHA) to penetrate through skin treated with a fractional laser; and (2) to assess the effectiveness of clinical laser scanning microscopy technologies in monitoring the effects of such treatment over time.

Methods: One area on a volunteer's arm was treated with a fractional erbium laser (Sciton Inc.

Hypohidrotic Ectodermal Dysplasia Milia Treatment With Fractional Carbon Dioxide Laser and Laser-Assisted Drug Delivery of Triamcinolone.

Hypohidrotic ectodermal dysplasia (HED) is a genetic disorder characterized by hypohidrosis, hypodontia, and hypotrichosis. Skin manifestations, including dyspigmentation and milia-like papules that coalesce into plaques, are difficult to treat. There is no cure for HED, therefore treatment is focused on managing symptoms and improving quality of life.

Economics of a Dermatology Practice.

Understanding the economics behind any medical practice comes down to one basic concept: Profit = Revenue - Expenses. This article aims to demystify the details that underlie this simple formula and to provide the budding dermatologist the information and the tools needed to determine their own profitability in the "real world."

Masculinized females adapt their fighting strategies to their opponent.

Many animal species show aggression to gain mating partners and to protect territories and other resources from competitors. Both male and female fruit flies of the species exhibit aggression in same-sex pairings, but the strategies used are sexually dimorphic. We have begun to explore the biological basis for the differing aggression strategies, and the cues promoting one form of aggression over the other.

Psoriasis severity: commonly used clinical thresholds may not adequately convey patient impact.

Background: Psoriasis severity is usually evaluated using quantitative and qualitative measures, including per cent body surface area (BSA) involvement, the Psoriasis Area and Severity Index (PASI) and the Dermatology Life Quality Index (DLQI), a patient-reported questionnaire. However, standardized definitions for psoriasis severity categories have not been well established. A PASI of 10 or 12 has remained the minimal severity threshold defining eligibility for psoriasis treatments.

Effect of Diode Laser (810 nm) Irradiation on Marginal Microleakage of Multi-mode Adhesive Resins in Class V Composite Restorations.

Some studies have shown that laser irradiation on unpolymerized adhesives can improve composite-dentin adhesion. The aim of the present study was to evaluate the effect of the diode laser (810 nm) on the microleakage of multi-mode adhesive systems at enamel and dentin margins of composite restorations. Classic class V boxes were prepared on 48 sound premolar teeth and randomly divided into 6 groups (n=16).

Examining the prior authorization process, patient outcomes, and the impact of a pharmacy intervention: A single-center review.

Background: Dermatology experiences a disproportionately high burden of prior authorizations (PAs).

Objective: To examine the effect of a centralized pharmacy intervention on the PA process and the impact of PAs on patient outcomes.

Methods: A retrospective review of PAs submitted for medications before and after implementation of pharmacy intervention was conducted.

Overview and update on biologic therapy for moderate-to-severe hidradenitis suppurativa.

Hidradenitis suppurativa (HS) is a frequently devastating inflammatory skin disorder. Although many treatments have been tried and tested to date, there is only one Food and Drug Administration-approved treatment option, adalimumab, which is currently indicated for moderateto- severe HS. Our understanding of the management of HS with biologic agents and with nonantibiotic and/ or antimicrobial systemic therapies continues to evolve.

Discordance Between Patient Reported Motivations to Seek Treatment for Psoriasis Compared to Television Advertisements.

Introduction: Despite a growing arsenal of therapies for psoriasis and, consequently, an increasing number of advertisements for these treatments, many psoriasis patients still remain untreated. While the primary treatment seeking motivations for these patients have been identified, it is unknown if the commercials for the medications designed to encourage patient engagement in treatment are relevant to these concerns.

Methods: Online databases for national television advertisements were searched for psoriasis treatment commercials broadcast between 2000 and 2018.

The effect of Z-primer on the shear bond strength of zirconia ceramic to dentin: .

Background: One of the major limitations of zirconia ceramic is the difficulty to adhere to dental. Said adhesion improves the marginal sealing of the restoration, minimizing microleakage. According to the limitation of zirconia ceramic bonding, zirconia primer enhances bond strengths to Zirconia, Alumina and Metal substrates.

Antiandrogen therapy with spironolactone for the treatment of hidradenitis suppurativa.

Background: Hormonal therapy is a potential treatment for hidradenitis suppurativa (HS). However, few data exist describing the efficacy of spironolactone in treatment of HS.

Objective: To assess whether spironolactone treatment improves HS disease severity and patient-reported pain.

Current guidelines for psoriasis treatment: a work in progress.

Psoriasis is a complex chronic autoimmune skin disease with multiple comorbidities that can have a considerable impact on quality of life (QoL). As therapeutic options evolve, physicians should look to treatment guidelines and consensus statements to keep their practice and management of psoriasis patients current with worldwide standards. This article reviews the most up-to-date general guidelines available for the management of psoriasis.