Publications by authors named "Goksenin Unluguzel Ustun"
Evaluating interleukin-6 levels and the rs1800795 variant in Turkish patients with COVID-19: a prospective cohort study.
Nucleosides Nucleotides Nucleic Acids
March 2024
Article Synopsis
- The study examines the link between the interleukin-6 (IL-6) gene variant rs1800795 and IL-6 levels in Turkish COVID-19 patients, focusing on how these factors relate to clinical severity.
- It involved a cohort of 148 patients, measuring IL-6 concentrations and genotyping, categorizing patients as asymptomatic, symptomatic, or in intensive care.
- Results indicated that the GG genotype and G allele were more frequent in asymptomatic patients, while symptomatic and ICU patients had higher frequencies of the C allele, suggesting a connection between genotype and the severity of COVID-19 symptoms.*
Aim: Microbiota of the reproductive tract may be associated with unexplained infertility in women. We aimed to determine the derangements of vaginal and endometrial microbiota related to unexplained infertility by real-time polymerase chain reaction (real-time PCR) microbiota analyses of vaginal and endometrial samples of the unexplained infertility patients and fertile women.
Materials And Methods: Twenty-six women with unexplained infertility and 26 age-matched fertile women were included.
This study aimed to examine the relationship between Hb A levels and the clinical course of coronavirus-19 (COVID-19) patients. Sixty-six COVID-19(+) patients with high Hb A and 46 with average Hb A and 30 COVID-19(-) patients with average Hb A were included. Hb A levels and parameters examined in COVID-19(+) patients were compared between groups, and correlation analysis was performed between these parameters and Hb A levels.
View Article and Find Full Text PDFBackground: Angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism may play a role in the pathogenesis of coronavirus-19 disease (COVID-19).
Objectives: Investigate the relationship between ACE I/D polymorphism and the clinical severity of COVID-19.
Design: Prospective cohort study.
Background/aim: The effectiveness of inhaled corticosteroids (ICSs) in cystic fibrosis (CF) is controversial. The aim of this study was to investigate the effect of an ICS on bronchial hyperreactivity (BHR), oxidative status, and clinical and inflammatory parameters in CF patients. Materials and methods: CF patients were randomized to receive either 2 mg/day nebulized budesonide or 0.
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