Publications by authors named "Gokhan Kocaman"

Adenocarcinomas, a common subtype of lung cancer, exhibit diverse histological patterns. In 2020, The International Association for the Study of Lung Cancer (IASLC) introduced a grading system emphasizing high-grade components, which has shown prognostic value. Spread through air spaces (STAS) is recognized as a prognostic feature increasing the risk of recurrence in lung cancer.

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Article Synopsis
  • The study examines the outcomes of complete thymectomy (CT) versus limited thymectomy (LT) in early stage thymoma patients who do not have myasthenia gravis.
  • 86 patients were analyzed, revealing that the CT group had more complications and deaths compared to the LT group, alongside a higher but not statistically significant recurrence rate.
  • The findings suggest that limited thymectomy could be a viable treatment option, yet future randomized controlled trials are needed for more conclusive evidence.
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Background: This study aims to evaluate the oncological results of primary and secondary chest wall tumors treated with curative resections and to investigate possible prognostic factors.

Methods: Between January 2010 and December 2021, a total of 77 patients (53 males, 24 females; median age: 59 years; range, 3 to 87 years) who underwent curative resection for malignant chest wall tumors were retrospectively analyzed. Each tumor was staged according to its histological type.

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Background: This study aims to assess the complications in post-novel coronavirus disease 2019 (COVID-19) thoracotomy patients and to evaluate the time interval between infection and surgery and the effect of vaccine timing and vaccine type in these patients.

Methods: Between May 2020 and January 2022, a total of 74 patients (34 males, 40 females; mean age: 54.5±13.

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Article Synopsis
  • - The study examines how various factors (like pathological stage and histological type) affect the likelihood of relapse in Stage I non-small cell lung cancer (NSCLC) patients after surgical treatment, with a focus on different machine-learning methods for prediction.
  • - After analyzing data from 268 patients, the DeepSurv model performed best in predicting recurrence during training, while the Random Survival Forest (RSF) model excelled in the test set.
  • - The findings suggest that machine-learning techniques can effectively predict NSCLC recurrence, helping doctors make informed decisions on additional treatments and follow-up care.
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Multiloculated thymic cyst is a cystic reaction of medullary epithelium to inflammatory process. In most cases, the exact cause of the inflammation is not known. Hodgkin lymphoma and multiloculated thymic cyst coexistence is a rare condition and may cause significant diagnostic difficulties.

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Article Synopsis
  • This study examined the impact of neoadjuvant therapy on survival outcomes in patients with locally advanced esophageal cancer, analyzing 143 patients over a nine-year period.
  • Results showed that patients who received neoadjuvant therapy had significantly higher five-year overall survival rates (52.9%) compared to those who did not receive it (8%).
  • The findings suggest that neoadjuvant therapy improves both overall survival and recurrence-free survival in these patients, making it a beneficial treatment option prior to surgery.
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Background: In this study, we aimed to evaluate the clinicopathological features of pulmonary inflammatory myofibroblastic tumor cases operated in our clinic.

Methods: A total of 17 inflammatory myofibroblastic tumor patients (5 males, 12 females; median age: 46 years) who were operated in our clinic between February 2000 and July 2019 were included. Data including sex, age, symptoms, accompanying diseases, tumor localization, tumor diameter, endobronchial extension, maximum standard uptake value of the tumors, surgery type, recurrence, and survival data were analyzed.

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  • Undifferentiated pleomorphic sarcoma, previously known as malignant fibrous histiocytoma, is a common type of soft tissue sarcoma in adults, derived from fibroblast and histiocytic cells.
  • It most frequently occurs in the lower limb, but can also be found in the upper limb and retroperitoneum, with rare occurrences on the chest wall.
  • The article presents a case study of a male patient with a large undifferentiated pleomorphic sarcoma located above the right scapula, highlighting its significance in surgical planning for chest wall masses.
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A 61-year-old male patient was hospitalized for the evaluation of a lung mass. The patient underwent right pneumonectomy. Although reverse-transcription polymerase chain reaction tests were negative for COVID-19, the diagnosis was supported by thoracic computed tomography.

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Background: In this study, we aimed to investigate the prognostic value of metabolic F-fluorodeoxyglucose positron emission tomography/computed tomography parameters in malignant pleural mesothelioma patients.

Methods: A total of 65 patients with malignant pleural mesothelioma (34 males, 31 females; median age: 60 years; range, 39 to 84 years) who underwent whole-body F-fluorodeoxyglucose positron emission tomography/computed tomography for staging before treatment between March 2008 and January 2018 were included. Relationships between clinicopathological factors and F-fluorodeoxyglucose positron emission tomography/computed tomography parameters and overall survival were evaluated using a log-rank test and Cox regression analysis.

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Background: In this study, we aimed to compare effectiveness of thoracic computed tomography versus intraoperative bimanual palpation in the detection of number of nodules in patients undergoing thoracotomy.

Methods: Between January 2011 and January 2019, a total of 157 patients (63 males, 94 females; mean age: 46.6±11.

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Introduction: Thoracic giant masses do not have a clear definition. In some publications, giant thoracic mass definition is used in tumors whose long axis is> 10 cm and in other publications covering more than 50% of the hemithorax. In this study, demographic data of patients with a massive resectable giant thoracic mass and the difficulties and experiences experienced in the peroperative process were reviewed with a general perspective.

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Background: Although tumor size is included in the definition of T descriptor in the tumor-node-metastasis (TNM) classification of many solid tumors, it is not considered for thymomas. This study aimed to assess the relationship of tumor diameters (the largest tumor diameter [LTD] and the mean tumor diameter [MTD]) with survival in thymoma patients undergoing surgical resection in a single center.

Methods: The study included 127 thymoma patients (age, 49.

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Pulmonary sclerosing pneumocytoma (PSP) is a rare tumor and the imaging appearance is usually a well-circumscribed nodule. Herein we present the clinicopathological features of a 25-year-old female patient with a 4 cm mass in the left upper lobe. She had undergone lobectomy with lymph node dissection with an incorrect intraoperative frozen section diagnosis of adenocarcinoma and diagnosed as a PSP with lymph node metastasis on permanent sections.

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Paraganglioma is a rare tumor originating from extra-adrenal chromaffin cells. Primary pulmonary paraganglioma can also be seen in pediatric patients. Due to its endobronchial localization, morphological features, and neuroendocrine immunohistochemical profile, primary pulmonary paraganglioma can be confused with carcinoid tumor.

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Background: This study aims to evaluate the outcomes of sublobar resections in patients with early-stage non-small cell lung cancer and to investigate the factors affecting survival.

Methods: Medical files of a total of 63 patients (52 males, 11 females; mean age 64 years; range, 39 to 81 years) who underwent sublobar resection for suspected or known early-stage non-small cell lung cancer between January 2001 and August 2013 were retrospectively reviewed. Data including demographic characteristics of the patients, comorbid conditions, smoking status, surgical margin, visceral pleura invasion, distance from surgical margin to tumor, tumor size, pathological N status, cell type, tumor localization, and recurrences were recorded.

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Partial anomalous pulmonary venous connection (PAPVC) is a rare congenital anomaly. Generally, it is seen on the right side and is associated with an atrial septal defect. Herein, we present a case of a 50-year-old male patient with a supracardiac type PAPVC detected during pneumonectomy for a right hilar mass.

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Intrapericardial goiter cases are only a few in the literature. We present a 53-year-old woman who was operated for 8-cm anterior mediastinal mass located completely intrapericardial and histopathological examination revealed an ectopic goiter. It may be difficult to distinguish between mediastinal masses within or outside the pericardium.

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Background: This study aims to identify the prognostic factors for stage I lung adenocarcinoma and to evaluate the surgical management of subsolid nodules.

Methods: The study included 133 patients (90 males, 43 females; mean age 64.9 years; range, 29 to 82 years) who had undergone operation in our clinic for stage I lung adenocarcinoma between January 2007 and December 2015.

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Esophageal carcinoma diagnosed during pregnancy is a rare occurrence. A 26-year-old pregnant patient was referred to our hospital with dysphagia. A thorough examination showed a tumor in the esophagus.

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Background: The ABO blood groups and Rh factor may affect the risk of lung cancer.

Materials And Methods: We analyzed 2,044 lung cancer patients with serologically confirmed ABO/Rh blood group. A group of 3,022,883 healthy blood donors of Turkish Red Crescent was identified as a control group.

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