An Algorithmic Approach to Minimally Invasive Management of Nontraumatic Chylothorax.

Chylothorax is a rare condition characterized by lymph accumulation in the pleural space. When it occurs independent of trauma, it is even more rare and difficult to treat as identification of lymphatic leak is unpredictable. In addition, treatment of this condition with conventional lymphangiography and thoracic duct embolization may not result in positive outcomes.

[Entrustable professional activities: a new proposal for the evaluation of the medical competencies].

Medical education migrated from a practice-based to a knowledge-based discipline after the publication of the Flexner Report. The emergence of competence-based medical education led to a greater standardization of teaching, allowing students to integrate knowledge, skills and attitudes for the execution of a given task. A challenge is the evaluation of learning.

Antinociceptive activity of Buddleja globosa (matico) in several models of pain.

Ethnopharmacological Relevance: Leaf extracts of Buddleja globosa (Buddlejaceae) are used in Chilean folk medicine for wound healing. The anti-inflammatory (topic and per os), analgesic (per os) effects and the antioxidant activity of Buddleja globosa were for the first time reported by us.

Aim Of The Study: Assess the antinociceptive activity of the methanol sequential and global extracts using complementary chemical and thermal models of pain, characterize pharmacologically the antinociception induced, evaluate seasonal influence to support Buddleja globosa medicinal use.

Analgesic, anti-inflammatory and antioxidant properties of Buddleja globosa, Buddlejaceae.

Ethnopharmacological Relevance: Buddleja globosa, known as "matico", is employed in Chile for wound healing.

Aim Of The Study: To validate the traditional use of the crude drug through in vivo and in vitro evaluation of the anti-inflammatory, analgesic and antioxidant properties of its extracts.

Materials And Methods: Sequential hexane, dichloromethane, methanol and total methanol extracts were studied using bioguided fractionation.