Publications by authors named "Goichi Endo"
Article Synopsis
- A rare case of peritonitis due to radiation enteritis is reported in an 82-year-old woman who had previously undergone surgery and radiotherapy for uterine cancer.
- The initial emergency surgery addressed a perforation in the ileum but faced complications due to suture failure linked to severe vascular changes from radiation damage.
- A subsequent reoperation involved more extensive intestinal resection, revealing less severe pathology in the remaining intestine, highlighting the need for careful surgical planning in patients with a history of abdominal radiation treatment.
Polymerase proofreading-associated polyposis, caused by germline variants in the exonuclease domains of POLD1 and POLE, is a dominantly inherited rare condition characterized by oligo-adenomatous polyposis and increased risk of colorectal cancer, endometrial cancer and brain tumours. We report the first Japanese case of polymerase proofreading-associated polyposis carrying a POLD1 variant. The proband was a Japanese woman who had undergone resections of early colorectal carcinomas repeatedly and a hysterectomy with bilateral oophorectomy for endometrial cancer, all of which were diagnosed within 2 years after the first colectomy at 49 year old.
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