Correlation of the nucleolar and karyoplasmic forms of RNA-polymerase was studied in the cell nuclei of the brain, liver, kidneys and the spleen of rats under normal conditions and after hydrocortisone administration. Hydrocortisone was found to stimulate both the nucleolar and karyoplasmic RNA synthesis. In the nuclei of different tissues correlation of the nuclear and karyoplasmic forms of RNA-polymerase changed under the effect of the hormone unequally.
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