Publications by authors named "Goethals L"

Background: Numerous strategies for preventing abusive head trauma (AHT) have been proposed, but controlled studies failed to demonstrate their effectiveness. Digital tools may improve the effectiveness of AHT prevention strategies by reaching a large proportion of the adult population.

Objective: This study aimed to describe the characteristics of videos of AHT prevention published on the internet, including their quality content, and to study their association with popularity.

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  • Chlamydia Trachomatis (CT) is the most common sexually transmitted infection in France, and this study evaluated the feasibility of systematic CT screening in Health Examination Centres (HECs) for young, sexually active individuals.
  • A total of 1,701 eligible participants were offered screening, with a high acceptance rate of 90.1%; the overall prevalence of CT infection was found to be 4.7%, with higher rates among women (6.4%) compared to men (3.4%).
  • The study revealed that deprivation significantly increased the likelihood of CT infection, particularly among women, highlighting the need to improve access to screening for disadvantaged populations to reduce health inequalities.
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  • A study was conducted to compare a modified radioimmunoassay (RIA) kit to two enzyme-linked immunosorbent assays (ELISA) methods for detecting anti-acetylcholine receptor (AChR) antibodies in a mouse model of myasthenia gravis (MG).
  • The modified RIA showed high sensitivity (84.1%) and perfect specificity (100%), indicating its effectiveness in identifying AChR antibodies.
  • The results suggest that using this modified RIA kit could streamline the antibody quantification process and minimize variability across different labs, as it doesn’t require time-consuming and costly antigen purification.
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  • Radiotherapy is an important cancer treatment, but research in low-income countries has some tough problems.
  • A 2022 survey provided new information on how these countries are dealing with radiotherapy and the funding they get.
  • The paper talks about new technology and ideas that can help improve cancer treatment in places that struggle with resources and emphasizes the need for more trained researchers in this field.
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Human epidermal growth factor receptor 2 (HER2) status is used for decision-making in breast carcinoma treatment. The status is obtained through immunohistochemistry or in situ hybridization. These two methods have the disadvantage of necessitating tissue sampling, which is prone to error due to tumor heterogeneity or interobserver variability.

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Studies on the bioavailability, serum levels, and absorption of hydrolyzable tannin compounds are lacking. In this study, we performed a pharmacokinetic trial, measured the serum levels of compounds in broilers that were reared with different feed added or not with tannins, and tested the digestibility of tannins throughout the intestinal tract. Only gallic acid and 4--methyl gallic acid were found in the serum.

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Background: The Emergency unit of the hospital (Department) (ED) is the fastest and most common way for most French general practitioners (GPs) to respond to the complexity of managing older adults patients with multiple chronic diseases. In 2013, French regional health authorities proposed to set up telephone hotlines to promote interactions between GP clinics and hospitals. The main objective of our study was to analyze whether the hotlines and solutions proposed by the responding geriatrician reduced the number of hospital admissions, and more specifically the number of emergency room admissions.

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The Cyberball is the most commonly employed paradigm for the investigation of the effects of social exclusion, also called ostracism. The analysis of event-related potentials (ERPs), short-term stimulus-induced fluctuations in the EEG signal, has been employed for the identification of time-sensitive neural responses to ostracism-related information. Changes in ERPs during the Cyberball are normally attributed to the effect of ostracism, but it has been argued that characteristics of the paradigm, not ostracism, are the driving force for these changes.

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Purpose: Sufficient radiotherapy (RT) capacity is essential to delivery of high-quality cancer care. However, despite sufficient capacity, universal access is not always possible in high-income countries because of factors beyond the commonly used parameter of machines per million people. This study assesses the barriers to RT in a high-income country and how these affect cancer mortality.

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The quantification of hydrolysable polyphenols such as gallic, ellagic acid and vescalagin by HPLC-DAD is classically run after methanol extraction as a reference solvent. Water extraction is usually discarded because of a lower obtention of total polyphenol content compared to methanol extraction. In our study, methanol was compared to water extraction in both the total polyphenol content method and the HPLC-DAD analysis.

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Amyloidoisis in patients with Waldenström macroglobulinemia (WM) mostly involves the heart, peripheral nerves and kidneys. Retroperitoneal amyloidosis is a rare finding. We describe a 62-year-old man with an incidental finding of a monoclonal gammopathy and elevated inflammatory parameters.

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Rationale: The ARS finance geriatric hotlines in order to improve the articulation between town medicine and the hospital. The objective of our study is to describe the health status and the care pathway of subjects aged over 75 years hospitalised in a geriatric short stay hospital via a geriatric hotline.

Materials And Methods: This prospective multicentre study included 1,451 subjects over 24 months.

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Since 2019, EU limits apply to cadmium (Cd) concentrations in cacao-derived food products. The dietary risk assessment leading to that regulation used consumption surveys aggregated to a limited number of chocolate product categories and did not consider differences in Cd bioaccessibility. Here, the cacao-related dietary Cd exposure in the Belgian population was estimated with higher resolution and accounting for bioaccessibility.

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It is known that high doses of various tannins could impair broiler growth, and this seems to be linked to a lowered protein availability. However, effects on protein digestion under the influence of hydrolysable tannins were minimal in previous research and literature. Other possible proposed reasons to explain reduced growth are scarce.

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Background: FDG-PET/CT has a high negative predictive value to detect residual nodal disease in patients with locally advanced squamous cell head and neck cancer after completing concurrent chemoradiotherapy (CCRT). However, the positive predictive value remains suboptimal due to inflammation after radiotherapy, generating unnecessary further investigations and possibly even surgery. We report the results of a preplanned secondary end point of the ECLYPS study regarding the potential advantages of dual time point FDG-PET/CT imaging (DTPI) in this setting.

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In 2 broiler trials, the effects of chestnut tannins on performance and meat quality (trial 1), and digestion (trial 2) were evaluated. In both trials, Ross 308 broilers received one of 2 basal diets: one basal diet contained corn and soy as main feed ingredients, while the challenge basal diet contained wheat, palm oil, and rapeseed meal. The composition of the basal diets was chosen to assess the interaction between chestnut tannins and diet composition.

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  • Falls impact one in three individuals over 65, leading to serious safety concerns, with physical exercise being the most effective prevention method.
  • A study aims to see if a social marketing program can boost attendance at balance workshops for people aged 60 and up in three regions of France over 18 months.
  • The initiative includes a communication campaign, distribution of flyers by local partners, and informational conferences, all approved by relevant ethics committees and funded by a foundation.
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Faced with an aging French population, the demand for unscheduled care is growing. In order to avoid referring elderly patients to emergency departments, which are unsuitable for them, the Regional Health Agencies have created telephone hot lines dedicated to geriatrics. They are exclusively accessible to general practitioners in order to obtain advice or a place in a geriatric hospital.

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In February 2021, France had more than 76,000 deaths due to COVID-19 and older adults were heavily affected. Most measures taken to reduce the impact of COVID-19 (quarantine, visit ban in nursing home, etc.) significantly influenced the lives of older adults.

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Previous cohorts studied the association of various types of physical activities with the incidence of cognitive disorders. The objective of this work was to analyze the association of leisure, domestic and professional physical activities with mild and moderate cognitive disorders in older people living in the community. We used retrospective data from the "FRéLE" (FRagilité: étude Longitudinale de ses Expressions) a longitudinal and observational study.

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Background: Noncommunicable diseases (NCDs) are the leading causes of death worldwide. They were responsible for 40 million of the 57 million deaths recorded worldwide in 2016. In Cameroon, epidemiological studies have been devoted to NCDs and their risk factors.

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Background: Falls are a significant source of morbidity in people aged 65 and over, affecting one in three people in this age group. The scientific evidence indicates that physical activity is the most effective method for preventing falls among seniors. Although public health professionals often use social marketing to design and plan successful interventions, its use to promote physical activity and prevent falls among older people remains low.

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  • COVID-19 has significantly impacted older adults, with initial reports of potential reinfection emerging in April 2020.
  • This report examines three cases of elderly women who experienced two separate infections of SARS-CoV-2, with a symptom-free period between episodes.
  • All three patients showed worsening health and radiological results during the second infection, leading to fatalities, highlighting concerns about the implications of reinfection and the need for testing in symptomatic cases.
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