Impact of implant design on the Forgotten Joint Score: a retrospective study comparing two contemporary knee designs.

This retrospective study was designed to assess two fixed bearing total knee design concepts and their clinical outcomes, particularly in Forgotten Joint Score-12 (FJS-12). Patients were assessed clinically using the Knee Society Score (KSS). Participants completed an FJS-12 and a short form of the Knee Injury and Osteoarthritis Outcome Score (KOOS-PS).

The Aqueous and Acetonitrile Bond Dissociation Free Energies of -Hydroxyphthalimide.

Widely cited values of 89 and 90.9 kcal/mol for the bond-dissociation free energy of -hydroxyphthalimide (NHPI) in water and acetonitrile, respectively, are in error. The sources of the errors leading to these values have been explored and corrected.

Primitive asteroids as a major source of terrestrial volatiles.

The origins of Earth's volatiles are debated. Recent studies showed that meteorites display unique mass-independent isotopic signatures of the volatile element Zn, suggesting that Earth's Zn originated from materials derived from different regions of the Solar System. However, these studies largely omitted meteorites from the differentiated planetesimals thought to represent the Earth's building blocks, which underwent melting and substantial volatile loss.

Seismic evidence for global basalt accumulation in the mantle transition zone.

The mantle's compositional structure reflects the thermochemical evolution of Earth. Yet, even the radial average composition of the mantle remains debated. Here, we analyze a global dataset of shear and compressional waves reflecting off the 410- and 660-km discontinuities that is 10 times larger than any previous studies.

The test-retest reproducibility of the multiple array probe Leiden in men with lower urinary tract symptoms.

Background: We aimed to study the test-retest reliability of the Multiple Array Probe Leiden (MAPLe), a multiple electrode probe designed to acquire and discriminate electromyography signals in the pelvic floor muscles, in men with lower urinary tract symptoms (LUTS).

Methods: Adult male patients with LUTS with sufficient knowledge of Dutch language, but without complications (e.g.

Slab to back-arc to arc: Fluid and melt pathways through the mantle wedge beneath the Lesser Antilles.

Volatiles expelled from subducted plates promote melting of the overlying warm mantle, feeding arc volcanism. However, debates continue over the factors controlling melt generation and transport, and how these determine the placement of volcanoes. To broaden our synoptic view of these fundamental mantle wedge processes, we image seismic attenuation beneath the Lesser Antilles arc, an end-member system that slowly subducts old, tectonized lithosphere.

Exposure to Infection in Individuals Who Are Newly Diagnosed with HIV and Antiretroviral-Naïve from Belém, Northern Brazil.

is one of the most prevalent sexually transmitted bacteria worldwide and may increase the risk of other sexually transmitted infections (STIs) including the human immunodeficiency virus (HIV). This study describes the seroprevalence of infection among antiretroviral-naïve patients who are newly diagnosed with HIV in the city of Belém, Pará, in the Amazon region of Brazil. A cross-sectional study was carried out between January 2018 and January 2019 in 141 people living with HIV/AIDS (PLHA) who were followed up in a specialized unit of the public health network of Pará.

Exploring Electrosynthesis: Bulk Electrolysis and Cyclic Voltammetry Analysis of the Shono Oxidation.

As electrochemistry continues to gain broader acceptance and use within the organic chemistry community, it is important that advanced undergraduate students are exposed to fundamental and practical knowledge of electrochemical applications for chemical synthesis. Herein, we describe the development of an undergraduate laboratory experience that introduces synthetic and analytical electrochemistry concepts to an advanced organic chemistry class. Experiments focus on the electrooxidative α-functionalization of carbamates, more generally known as the Shono oxidation, and include cyclic voltammetry analysis of two cyclic carbamates and a constant current bulk electrolysis reaction.

Posterior chamber toric implantable collamer lenses vs LASIK for myopia and astigmatism: systematic review.

This systematic review compares the visual and refractive outcome of laser in situ keratomileusis with (toric) implantable collamer lens (ICL) in the treatment of myopic astigmatism. An electronic literature search led to 19 comparative articles. Refractive outcome, efficacy, safety, predictability, and stability as well as differences in contrast sensitivity and higher-order aberrations (HOAs) were analyzed for moderate (-3 to -6 diopters [D]) and high (≥-6 D) myopia.

A systematic review on the role of trust in the water governance literature.

Trust is generally considered to play a key enabling role in water governance. Despite this notion, there have been no systematic assessments examining the way in which the literature on water governance engages with 'trust'. Our article fills this gap by providing an overview of the way in which this literature has engaged with trust as a conceptual lens, analytical device and empirical phenomenon.

Resolution Learning in Deep Convolutional Networks Using Scale-Space Theory.

Resolution in deep convolutional neural networks (CNNs) is typically bounded by the receptive field size through filter sizes, and subsampling layers or strided convolutions on feature maps. The optimal resolution may vary significantly depending on the dataset. Modern CNNs hard-code their resolution hyper-parameters in the network architecture which makes tuning such hyper-parameters cumbersome.

Deriving the Turnover Frequency of Aminoxyl-Catalyzed Alcohol Oxidation by Chronoamperometry: An Introduction to Organic Electrocatalysis.

Organic electrosynthesis is an increasingly popular tool for driving and probing redox reactions. Recent advances in this field often employ an electrocatalyst to enhance the selectivity and efficiency of electrochemical reactions. A laboratory experiment was developed to introduce students to relevant mechanistic techniques in electrochemistry for analysis of electrocatalytic reactions using aminoxyl-catalyzed alcohol oxidation as a case study.

Subduction history of the Caribbean from upper-mantle seismic imaging and plate reconstruction.

The margins of the Caribbean and associated hazards and resources have been shaped by a poorly understood history of subduction. Using new data, we improve teleseismic P-wave imaging of the eastern Caribbean upper mantle and compare identified subducted-plate fragments with trench locations predicted from plate reconstruction. This shows that material at 700-1200 km depth below South America derives from 90-115 Myr old westward subduction, initiated prior to Caribbean Large-Igneous-Province volcanism.

Author Correction: Variable water input controls evolution of the Lesser Antilles volcanic arc.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Rapid subduction initiation and magmatism in the Western Pacific driven by internal vertical forces.

Plate tectonics requires the formation of plate boundaries. Particularly important is the enigmatic initiation of subduction: the sliding of one plate below the other, and the primary driver of plate tectonics. A continuous, in situ record of subduction initiation was recovered by the International Ocean Discovery Program Expedition 352, which drilled a segment of the fore-arc of the Izu-Bonin-Mariana subduction system, revealing a distinct magmatic progression with a rapid timescale (approximately 1 million years).

Blockade of angiotensin AT receptors prevents arterial remodelling and stiffening in iron-overloaded rats.

Background And Purpose: Damage to the vasculature caused by chronic iron-overload in both humans and animal models, is characterized by endothelial dysfunction and reduced compliance. In vitro, blockade of the angiotensin II AT receptors reversed functional vascular changes induced by chronic iron-overload. In this study, the effect of chronic AT receptor blockade on aorta stiffening was assessed in iron-overloaded rats.

Flexibility exercise training for adults with fibromyalgia.

Background: Exercise training is commonly recommended for adults with fibromyalgia. We defined flexibility exercise training programs as those involving movements of a joint or a series of joints, through complete range of motion, thus targeting major muscle-tendon units. This review is one of a series of reviews updating the first review published in 2002.

Mixed exercise training for adults with fibromyalgia.

Background: Exercise training is commonly recommended for individuals with fibromyalgia. This review is one of a series of reviews about exercise training for fibromyalgia that will replace the review titled "Exercise for treating fibromyalgia syndrome", which was first published in 2002.

Objectives: To evaluate the benefits and harms of mixed exercise training protocols that include two or more types of exercise (aerobic, resistance, flexibility) for adults with fibromyalgia against control (treatment as usual, wait list control), non exercise (e.

Earthquakes track subduction fluids from slab source to mantle wedge sink.

Subducting plates release fluids as they plunge into Earth's mantle and occasionally rupture to produce intraslab earthquakes. It is debated whether fluids and earthquakes are directly related. By combining seismic observations and geodynamic models from western Greece, and comparing across other subduction zones, we find that earthquakes effectively track the flow of fluids from their slab source at >80 km depth to their sink at shallow (<40 km) depth.

Fully convolutional architecture vs sliding-window CNN for corneal endothelium cell segmentation.

Background: Corneal endothelium (CE) images provide valuable clinical information regarding the health state of the cornea. Computation of the clinical morphometric parameters requires the segmentation of endothelial cell images. Current techniques to image the endothelium in vivo deliver low quality images, which makes automatic segmentation a complicated task.

Electrochemical Aminoxyl-Mediated α-Cyanation of Secondary Piperidines for Pharmaceutical Building Block Diversification.

Secondary piperidines are ideal pharmaceutical building blocks owing to the prevalence of piperidines in commercial drugs. Here, we report an electrochemical method for cyanation of the heterocycle adjacent to nitrogen without requiring protection or substitution of the N-H bond. The reaction utilizes ABNO (9-azabicyclononane N-oxyl) as a catalytic mediator.

Strong plates enhance mantle mixing in early Earth.

In the present-day Earth, some subducting plates (slabs) are flattening above the upper-lower mantle boundary at ~670 km depth, whereas others go through, indicating a mode between layered and whole-mantle convection. Previous models predicted that in a few hundred degree hotter early Earth, convection was likely more layered due to dominant slab stagnation. In self-consistent numerical models where slabs have a plate-like rheology, strong slabs and mobile plate boundaries favour stagnation for old and penetration for young slabs, as observed today.

Scoping Review of Dance for Adults With Fibromyalgia: What Do We Know About It?

Background: Fibromyalgia is a chronic disorder characterized by widespread muscular tenderness, pain, fatigue, and cognitive difficulties. Nonpharmacological treatment options, such as physical activity, are important for people with fibromyalgia. There are strong recommendations to support engagement in physical activity for symptom management among adults with fibromyalgia.

Compositional heterogeneity near the base of the mantle transition zone beneath Hawaii.

Global seismic discontinuities near 410 and 660 km depth in Earth's mantle are expressions of solid-state phase transitions. These transitions modulate thermal and material fluxes across the mantle and variations in their depth are often attributed to temperature anomalies. Here we use novel seismic array analysis of SS waves reflecting off the 410 and 660 below the Hawaiian hotspot.