The Relationship Between Medical Error Attitudes of Surgical Nurses and Evidence-Based Work Environment.

Background: It is important for health care professionals to use evidence-based practice during  surgical procedures to ensure patient safety and prevent medical errors.

Aims: The aim of this study was to examine the relationship between surgical nurses' perceptions of their work environment's support for evidence-based practice and their attitudes toward medical errors.

Methods: The descriptive cross-sectional study was conducted between February and May 2023.

Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage.

Extracellular vesicles (EVs) are widely investigated for their implications in cell-cell signaling, immune modulation, disease pathogenesis, cancer, regenerative medicine, and as a potential drug delivery vector. However, maintaining integrity and bioactivity of EVs between Good Manufacturing Practice separation/filtration and end-user application remains a consistent bottleneck towards commercialization. Milk-derived extracellular vesicles (mEVs), separated from bovine milk, could provide a relatively low-cost, scalable platform for large-scale mEV production; however, the reliance on cold supply chain for storage remains a logistical and financial burden for biologics that are unstable at room temperature.

The Effect of Genotype Differences on Cardiac Involvement in Cases Diagnosed with Duchenne Muscular Dystrophy.

Aim:  Duchenne muscular dystrophy (DMD) is the most frequently seen muscular disease in childhood. Cardiac involvement is extremely important in terms of morbidity and mortality in these patients. Different studies have shown that mutations occurring in various exons are cardioprotective or increase cardiac involvement in DMD cases.

Fertility, pregnancy outcomes, and disease activity during pregnancy in patients with juvenile idiopathic arthritis: a descriptive study.

To investigate the fertility status, pregnancy outcomes, and disease activity during and after pregnancy in patients with juvenile idiopathic arthritis (JIA) currently being followed up at an adult rheumatology clinic. This study included 141 adult patients diagnosed with according to the International League of Associations for Rheumatology criteria, who are now monitored at an adult rheumatology clinic. Data on demographics, disease characteristics, medication history, fertility status, and pregnancy outcomes were collected through medical records and patient interviews.

Evaluating the prognostic value of DECAF score and procalcitonin in patients with COPD exacerbation.

Objectives: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) frequently result in emergency department (ED) visits, necessitating accurate risk stratification. The aim of this study was to evaluate and compare the prognostic utility of the DECAF score and serum procalcitonin levels in predicting clinical outcomes in patients with AECOPD.

Methods: This retrospective cohort study encompassed AECOPD patients presenting to the ED over a three-year period who had serum procalcitonin levels measured.

Longitudinal analysis of anthropometric measures over 5 years in patients with Friedreich ataxia in the EFACTS natural history study.

Background: Friedreich ataxia is a rare neurodegenerative disorder caused by frataxin deficiency. Both underweight and overweight occur in mitochondrial disorders, each with adverse health outcomes. We investigated the longitudinal evolution of anthropometric abnormalities in Friedreich ataxia and the hypothesis that both weight loss and weight gain are associated with faster disease progression.

Ultrasonographic Evaluation of Solid Organ Sizes in Children with Primary Malnutrition: A Preliminary Study.

Malnutrition is a common health problem affecting overall body functions, growth, and development. The aim of the present study was to explore any potential changes in solid organ sizes due to malnutrition and, if so, their correlation with the degree of malnutrition. Solid organ sizes (liver, spleen, and kidneys) in patients with primary malnutrition were measured prospectively using ultrasonography.

Genome-wide discovery of underlying genetic factors associated with fresh and frozen-thawed semen traits in composite ram breeds exhibiting different cryotolerance.

Fewer studies investigate the effects of underlying genetic factors related to semen characteristics, significantly affecting sheep farm profitability. This study aimed to identify single nucleotide polymorphisms (SNP) and genomic regions associated with fresh and frozen-thawed semen traits in rams with low (Hasak) and high (Hasmer) cryotolerance. Semen collected from 11 (5 Hasak with low and 6 Hasmer with high cryotolerance) rams cryopreserved in 0.

Molecular Detection and Phylogenetic Analysis of Orf Virus From Dermatological Lesions in the Teats of Goats.

Background: The orf virus (ORFV) is a viral pathogen that primarily causes contagious ecthyma in humans and different ruminants. The infection, which is common worldwide, causes large-scale economic losses to animal breeders.

Objective And Methods: In this study, tissue samples collected from eight randomly selected goats with dermatological lesions on the teats were examined in different goat herds.

Effect of a Wrist Harmonic Liquid Tremor Absorber-Damping on the Upper Extremity Essential Tremor.

Background: Essential tremor (ET) is a common type of tremor. Previous research has shown that wearable orthoses and biomechanical loading methods can suppress tremors.

Objective: This study aims to investigate the effect of a harmonic liquid dampener on upper extremity ET.

Predictive Modeling Is a Reliable Indicator in Determining Excessive Renal Mobility Single-Center Randomized Study.

Excessive kidney mobility is an underestimating challenge for surgeons during retrograde intrarenal surgery (RIRS) and extracorporeal shock wave lithotripsy (ESL). There is no technique approved as a gold standard procedure for reducing excessive kidney mobility. The study aimed to uncover predictive factors for determining excessive renal mobility by utilizing clinicodemographic characteristics and noncontrast computed tomography (NCCT) data.

Modification of Gene Expression Involved in Alkaloid Production in Opium Poppy by VIGS Combined With Pretreatment of Macerozyme Enzyme.

L., a medicinal plant renowned for its pharmaceutical alkaloids, has captivated scientific interest due to its rich secondary metabolite profile. This study explores a novel approach to manipulating alkaloid biosynthesis pathways by integrating virus-induced gene silencing (VIGS) with macerozyme enzyme pretreatment.

Ebstein's anomaly in children and young adults: clinical features, arrhythmia, surgical management, and factors affecting arrhythmia and mortality.

Background: Ebstein's anomaly represents 40% of congenital tricuspid valve abnormalities. Studies about paediatric Ebstein's anomaly patients are limited.

Aim: To evaluate clinical characteristics, treatment (medical/arrhythmia ablation/surgical) results, and outcome of Ebstein's anomaly patients, and to determine factors affecting arrhythmia presence and mortality.

Artificial Doctors: Performance of Chatbots as a Tool for Patient Education on Keratoconus.

Purpose: We aimed to compare the answers given by ChatGPT, Bard, and Copilot and that obtained from the American Academy of Ophthalmology (AAO) website to patient-written questions related to keratoconus in terms of accuracy, understandability, actionability, and readability to find out whether chatbots can be used in patient education.

Methods: Twenty patient-written questions obtained from the AAO website related to keratoconus were asked to ChatGPT, Bard, and Copilot. Two ophthalmologists independently assessed the answers obtained from chatbots and the AAO website in terms of accuracy, understandability, and actionability according to the Structure of Observed Learning Outcome taxonomy, Patient Education Materials Assessment Tool-Understandability, and Patient Education Materials Assessment Tool-Actionability tests, respectively.

Improving Psychiatry Services with Artificial Intelligence: Opportunities and Challenges.

Mental disorders are a critical global public health problem due to their increasing prevalence, rising costs, and significant economic burden. Despite efforts to increase the mental health workforce in Türkiye, there is a significant shortage of psychiatrists, limiting the quality and accessibility of mental health services. This review examines the potential of artificial intelligence (AI), especially large language models, to transform psychiatric care in the world and in Türkiye.

Impact of sub-lethal Aclonifen intoxication on biochemical and stress markers on : an integrative assessment of multi-biomarker responses.

Aclonifen is a diphenyl ether herbicide being included in the list of priority substances. Nevertheless, the data related to its sublethal effects on fish are limited. Therefore, the present study has been carried out to investigate the toxic effects of aclonifen in juvenile following 24, 48, 72 and 96 hours of application to sublethal concentrations of 12.

Is there a significant relationship between the empowering leadership behaviors of school principals and the psychological resilience of teachers? Understanding the moderating effects of gender and length of time spent with the school principal.

The psychological resilience of teachers has gained significant attention due to its positive effects on schools and students. This cross-sectional quantitative study investigates the moderating roles of gender and the length of time spent with the school principal in the relationship between principals' empowering leadership behaviors and teachers' psychological resilience. Data were collected from 362 teachers working in public primary, secondary, and high schools in Siirt, Türkiye.

Mouse Intestinal Organoid Culture Protocol.

The discovery of leucine-rich-containing G-protein-coupled receptor 5 (Lgr5) as an intestinal adult stem cell marker had blazed a trail in stem cell biology and laid the foundations of modern organoid technology. Up to date, several well-established intestinal organoid protocols have been reported in the literature from different sources, including adult and induced pluripotent stem cells. Here, we demonstrate a BALB/c mouse-derived intestinal organoid culture protocol, passaging, and cryopreservation procedures.

Predicting mortality in adults hospitalized with multiple trauma: Can the BIG score estimate risk?

Background: This study aimed to compare the predictive performance of the BIG score (base deficit + [2.5 × international normalized ratio (INR)] + [15 - Glasgow Coma Scale (GCS)]) for in-hospital mortality in adult patients with multiple trauma against other scoring systems, including the Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), and Injury Severity Score (ISS).

Methods: A retrospective single-center study was conducted, including 563 adults (aged ≥18 years) with multiple trauma who were admitted to the emergency department and hospitalized between January 2022 and December 2023.

Professional values and factors affecting these values in midwifery students.

This study investigated the professional values of midwifery students and the factors influencing these values. Conducted from January 6 to March 6, 2021, it involved 715 midwifery students who participated voluntarily. Data was collected using a Descriptive Data Sheet and the Professional Values of Midwives Scale.

Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation.

: Studies have shown that inflammation markers can be used as prognostic tools in predicting acute ischemic stroke. In this study, we conducted a comparison of several inflammation scores in predicting left atrial thrombosis (LAT) in patients with ischemic stroke without AF. : In this single-center, retrospective study, we included 303 consecutive patients with ischemic stroke.

Impact of Neutrophil-to-Lymphocyte Ratio on Stroke Severity and Clinical Outcome in Anterior Circulation Large Vessel Occlusion Stroke.

The prognostic value of the neutrophil-lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates the relationship between admission NLR, stroke severity and 90-day outcomes in patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. A retrospective multicenter study was conducted with 1082 patients treated with mechanical thrombectomy for acute ischemic stroke.

How are the Attitudes Towards Aging and Aging and Death Anxiety in Individuals Over 65 Years of Age With Chronic Diseases?: A Cross-Sectional and Analytical Study.

This study examined the relationship between attitudes toward aging and death anxiety in individuals aged 65 and older with chronic diseases. The study involved 169 participants. Data were collected using Personal Information Form, Turkish Death Anxiety Scale (TDAS), and Attitudes toward Ageing and Elderliness Scale (ATAES).