Publications by authors named "Goekhun Arican"

Biomechanical properties of a mandibular first molar with different cavity designs [traditional access cavities (TEC-I & TEC-II), ninja access cavity (NEC), conservative access cavity (CEC), truss access cavity (Tr-EC), caries-driven access cavity (Cd-EC), caries-driven truss access cavity (Cd-TrEC)] were compared using finite element (FE) analysis. Models were subjected to three different loads. The highest stress distribution was observed on the enamel surface of the Cd-EC design and the dentin surface of the TEC-II.

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Purpose: Blood loss and pain management are significant concerns in total knee arthroplasty (TKA). Tranexamic acid (TA) and cryotherapy have been used separately to address these issues, but their comparative effectiveness is not well studied. This study aimed to evaluate the efficacy of intravenous TA and cryotherapy in reducing blood loss and improving clinical outcomes after TKA.

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Music- and distraction-induced pain reduction have been investigated extensively, yet the main mechanism underlying music-induced analgesia remains unknown. In this study, to assess whether music-induced analgesia primarily operates through cognitive modulation, we used the cold pressor task and objectively compared the pain tolerances of participants in a four-group between-subjects design: a music group that listened to a music piece in the absence of any tasks, a music-and-attention-to-music group that listened to the same piece while also rating the arousal levels in the music, a music-and-attention-to-pain group that rated their pain levels while listening to the same piece, and a silence group as control. The group passively exposed to music playback did not show significantly higher pain tolerance compared to the silence group.

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Pheochromocytoma is a rare tumor originating from the adrenal gland, characterized by the secretion of catecholamines. Due to the risk of hypertensive crises associated with catecholamine release, surgical procedures in pheochromocytoma patients are risky. In this case report, laparoscopic appendectomy for acute appendicitis in a patient who has pheochromocytoma will be presented.

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  • - This study assessed the effects of the pain medications phenyramidol and diclofenac on bone healing in a rat model of femur fractures, focusing on radiological, histological, and biomechanical evaluations over time.
  • - A total of 72 male rats were divided into groups receiving different treatments (phenyramidol, diclofenac, both, or none) and were examined at various postoperative intervals (15, 30, 45 days) for their healing progress.
  • - The findings indicated that both medications alone hindered fracture healing, but their combined use was somewhat less detrimental. While there were some differences in healing outcomes among the groups, overall, histological assessments showed no significant improvement in bone healing with either medication
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  • This study evaluated the effectiveness of first-line antiseizure medications in 1003 newly diagnosed children with epilepsy, focusing on their drug efficacy rates and resistance levels over an average follow-up period of 22 months.
  • The first-drug efficacy rate was approximately 67% for children with focal-onset seizures and 66% for those with generalized-onset seizures, while the overall first-drug failure rate was reported at 33%.
  • Notably, children with structural etiology exhibited a significantly lower first-drug efficacy rate of 53% and a 30% rate of drug-resistant epilepsy, compared to higher success rates in those with defined epilepsy syndromes (79%).
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  • The study compared the capsular volume of patients with shoulder instability to those without using MR arthrography, aiming to create a reliable screening method.
  • In a retrospective analysis of 21 patients with shoulder instability and 21 controls, volumetric measurements of various shoulder components were taken from 3D MR images.
  • Results showed that the instability group had a significantly larger total joint volume and greater volumes in specific shoulder areas compared to the control group, suggesting that 3D volumetric assessment can aid in clinical evaluations and treatment decisions for shoulder instability.
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This study aimed to evaluate the relationship between SLAP lesions and the shoulder joint capsule thickness via MR arthrography. Understanding the relationship between SLAP lesions and the joint capsule thickness is important because an increased capsule thickness may indicate chronic inflammation and contribute to persistent pain and dysfunction. These findings have significant clinical implications for the diagnosis, management, and treatment strategies of shoulder joint pathologies.

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Objectives: The aim of this study was to identify the biomechanical and histopathological changes of ligamentum mucosum (LM) in patients with intact versus ruptured anterior cruciate ligament (ACL).

Patients And Methods: A total of 67 patients (45 males, 22 females; mean age: 33.2±7.

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Objective:  This study aimed to investigate the effect of the low-intensity pulsed ultrasound (LIPUS) on the healing of Achilles tendinopathy in a rat model induced by type 1 collagenase.

Methods:  The study was conducted on 144 Achilles tendons of 72 Wistar albino female rats with typical activity and weighing 300-350 g. The model of Achilles tendinopathy was created by injecting type 1 collagenase.

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Purpose: This study aimed to compare the effectiveness of Pulsed Radiofrequency Ablation (PRFA) and surgery for treating chronic plantar fasciitis, focusing on pain relief and functional outcomes.

Methods: A prospective study involved 30 patients with chronic plantar fasciitis unresponsive to 12 months of conservative treatment. Patients were divided into PRFA (n = 17) and surgical (n = 13) groups.

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Objectives: This study aimed to investigate the influence of access cavity designs on the mechanical properties of a single-rooted mandibular first premolar tooth under various static loads using a finite element analysis.

Materials And Methods: 3-dimensional FEA designs were modeled according to the access cavity designs: an intact tooth (control), traditional access cavity (TEC-I), traditional access cavity with Class-II mesio-occlusal cavity design (TEC-II), conservative access cavity (CEC), ninja access cavity (NEC), caries-driven access cavity (Cd-EC), buccal access cavity (BEC) and bucco-occlusal access cavity (BOEC). After the simulated access cavity preparations, root canal treatment was simulated and three different static loads which mimicked oblique and vertical mastication forces were applied to the models.

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Purpose: In this study, we aimed to investigate the effects of hyperbaric oxygen therapy and enoxaparin sodium, which are known to accelerate bone tissue healing as well as tendon and soft tissue healing, on the healing of Achilles tendon rupture.

Methods: Thirty-six rats were used in the present study. All rats were divided into groups of nine.

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Objectives: We investigated the efficacy of the erector spinae plane block, which has been proven to be effective in breast surgery, on intraoperative opioid consumption and postoperative analgesia when administered in different volumes with the same concentration of local anesthetic.

Methods: This study is designed as randomized, prospective, and double-blind. Seventy patients aged between 18-70 years, undergoing ASA I-III elective breast surgery, were included.

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This study was carried out to investigate the macroanatomical, morphometric, histological, and electron microscopic characteristics of the uropygial gland in adult male and female turkeys (Meleagris gallapovo).

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Article Synopsis
  • The study investigated how various factors like living environment (urban vs. rural), time between fractures, and health conditions relate to non-simultaneous contralateral hip fractures in older adults.
  • A total of 107 patients aged 65 and older with proximal femur fractures were analyzed, revealing a mean age of 83.76 years and an average interval of 28.3 months between their fractures.
  • Key findings indicated that rural patients had different first fracture locations, and specific comorbidities like heart failure and osteoporosis were linked to shorter intervals between fractures, highlighting significant risk factors for subsequent hip fractures.
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Purpose: The aim of this study was to evaluate how the pie-crusting technique affects clinical and radiological outcomes in patients undergoing arthroscopic partial meniscectomy.

Methods: A total of 68 patients with Kellgren-Lawrence (K-L) grade 2 who underwent arthroscopic partial meniscectomy between 2015 and 2021 were evaluated and divided into two groups as arthroscopic partial meniscectomy (36 patients) and arthroscopic partial meniscectomy with pie-crusting (32 patients) according to whether the pie-crusting technique was applied or not. All patients were evaluated at a minimum 2-year follow-up in terms of Lysholm score, Tegner activity score, International Knee Documentation Committee (IKDC) score and Visual Analogue Scale (VAS) score.

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  • Fracture healing involves complex interactions among physical, biological, and chemical factors, and although research is growing, its mechanism is not completely understood.
  • This study examined the effects of the COVID-19 treatments favipiravir and hydroxychloroquine on fracture healing using 48 male Wistar rats, which were analyzed at the 2nd and 4th weeks for radiological and histological changes.
  • Results showed a significant early negative impact of favipiravir on bone repair, but potential positive effects later on, while hydroxychloroquine did not significantly influence fracture healing.
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Background: The odours of different body parts and structures, such as external genitalia, female urine, ventral tail radix, infraorbital sinus and interdigital sinus, have a strong attractiveness for rams. The sinus interdigitalis is considered an important trail gland for sexual behaviour, as its odour is included in the list of strongly attractive structures for male animals during the breeding season, being important in pheromone production.

Objectives: In the present study, the effects of sex and breeding season on the morphological and histological structure of the interdigital gland were investigated in Hamdani crossbred sheep (Ovis aries).

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  • The study aimed to evaluate the effectiveness of biceps tenodesis (BT) at different pressure levels during superior capsule reconstruction (SCR) in rabbits with massive rotator cuff tears.
  • Thirty rabbits were divided into three groups based on pressure applied during the BT procedure, with results assessed after a 4-week follow-up via histopathological analysis.
  • Group 2, which experienced the lowest pressure, showed significantly reduced extracellular matrix, cellularity levels, and vascularity compared to the other groups, suggesting that lower pressure exposure may enhance the success of BT in SCR.
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Although the Achilles tendon is the largest and strongest tendon in the body, healing of the Achilles tendon is the most common injury, and this process is difficult due to poor tendon circulation; moreover, the underlying mechanism has not been fully elucidated. In our study, we aimed to investigate the effects of pentoxifylline and alpha-tocopherol administered separately or in combination on rats with Achilles tendon injury. Forty-eight male Wistar rats weighing 230 ± 30 g were used in the study.

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Background: Suture and screw fixations are widely used to treat tibial eminence fractures (TEFs). Although a few biomechanical and clinical studies have compared suture fixation (SF) and screw fixation in the treatment of TEFs in children, no comparative clinical studies are available regarding headless screw fixation (HSF).

Purpose: To evaluate the clinical and functional outcomes of children with TEF who underwent SF and HSF.

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Background: In order to perform a full surgical resection on non-palpable breast lesions, a current method necessitates correct intraoperative localization. Additionally, because it is an important prognostic factor for these patients, the examination of the lymph node status is crucial.

Objective: The aim of this study was to evaluate the efficiency of the sentinel node and occult lesion localization (SNOLL) technique in localizing nonpalpable breast lesions together with sentinel lymph node (SLN) using a single radiotracer, that is, nanocolloid particles of human serum albumin (NC) labeled with technetium-99m (99mTc).

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Background: Febrile seizures are the most common form of convulsive disorder in childhood. The mechanisms underlying the pathogenesis of febrile seizure remain unclear.

Objective: The aim of this study was to assess the immunoglobulin (IG) sub-group levels in children with febrile seizures.

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