Advantage of Hybrid F-Fluoride Positron Emission Tomography/Computed Tomography to Diagnose Malignant Rib Invasion by Pleural Metastasis in a Background of Reactive Periostitis.

Diffuse osteoblastic activity in the ribs on bone scan is seen in association with pleural thickening. Irrespective of the pleural pathology, this represents benign finding caused by pleural hyperemia or reactive periostitis, with preserved cortical integrity. However, malignant involvement of the ribs can occur by local invasion of pleural malignancy causing cortical lysis.

Parathyroid Carcinoma - A Malignant Cause of Metabolic Skeletal Super Scan on Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.

Excessive abnormal tracer uptake in active tracer avid organ(s) with the suppression of physiological background tracer distribution is termed as super scan. Herein, we present an F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT), where the metabolic pattern of skeletal super scan with coexistent parathyroid tumor was seen giving rise to the suspicion of primary hyperparathyroidism. It was subsequently diagnosed as a case of parathyroid carcinoma.

Obstructive Jaundice: An Unusual Presentation of Neuroendocrine Differentiation in Prostatic Adenocarcinoma.

An elderly male on androgen deprivation therapy for prostatic adenocarcinoma presented with obstructive jaundice. Since biopsy from the head of the pancreas showed neuroendocrine carcinoma (NEC), he was diagnosed with second primary pancreatic NEC. Ga-68 DOTANOC positron emission tomography/computed tomography (PET/CT) done subsequently showed enlarged mildly DOTANOC-avid retroperitoneal nodes infiltrating the pancreas.

Delayed 68Ga-PSMA PET/CT Image-Guided Biopsy for Low-Grade Adenocarcinoma in Benign Prostatic Hyperplasia.

Image-guided biopsy of prostate with multiparametric MRI is being adopted in the workup of prostate adenocarcinoma (PAC). 68Ga-PSMA PET/CT-guided biopsy has also been shown to be equally sensitive in the evaluation of higher-grade tumors with increased PSMA expression. The sensitivity of 68Ga-PSMA PET/CT, however, reduces with lesser PSMA expression in low-grade PAC.

De Novo Presentation of Sarcoidosis on Restaging FDG PET/CT in Rectal Carcinoma With Self-resolution.

Sarcoidosis is a systemic disorder of unknown etiology characterized by development of noncaseating granulomas in more than 1 organ system. Development of sarcoidosis during or immediately after chemotherapy and immunotherapy is not uncommon. We present a 61-year-old woman in whom restaging F-FDG PET/CT detected asymptomatic sarcoidosis after neoadjuvant chemoradiotherapy for carcinoma rectum, which resolved spontaneously by the end of adjuvant chemotherapy with no specific treatment.