Occurrence and distribution of extended-spectrum β-lactamase in clinical isolates at Ho Teaching Hospital in Ghana.

Objective: This study determined the occurrence and distribution of Extended Spectrum β-Lactamase (ESBL) genotypes of isolates in Ho Teaching Hospital, Ghana.

Design: A cross-sectional study.

Setting: A single centre study was conducted at Ho Teaching Hospital of Ghana.

Carbapenemase Production and Detection of Colistin-Resistant Genes in Clinical Isolates of from the Ho Teaching Hospital, Ghana.

Background: Effective and successful treatment of infectious diseases is a significant gain in clinical settings. However, resistance to antibiotics, especially the last-resort medicines, including carbapenems and colistin is on the rise.

Aim: The aim of this study was to detect carbapenemase production and colistin-resistant genes in clinical isolates of .

Burden of Fluoroquinolone Resistance in Clinical Isolates of at the Ho Teaching Hospital, Ghana.

Background: The growing burden of antibiotic resistance is a threat to the management of infections. Infections by Escherichia coli are routinely treated with fluoroquinolone antimicrobial agents. Due to their frequent use, there has been increasing resistance to these drugs.

A Comparative Study of the Epidemiology of Treponemal Infection in the Volta and Oti Regions of Ghana: A Five-Year Multisite Parallel Population-Based Analysis vis-à-vis the Sentinel Survey.

Treponemal infections can be blood-borne with great public health consequences. This study is aimed at comparatively describing the five-year (2013-2017) regional epidemiology of treponemal infection using pregnant women in the sentinel survey and apparently healthy blood donors as a proxy for the general population at four sentinel sites in the Volta and Oti Regions of Ghana. We analyzed retrospective data from 17,744 prospective blood donors aged 18 to 58 years and 7,817 pregnant women in a sentinel survey with ages from 15 to 49 years at Hohoe, Ho, Tongu, and Krachi West sentinel sites in the Volta and Oti Regions.

Investigating the Anticonvulsant Properties of Aqueous Ethanolic Extracts of the Leaves, Roots, and Fruits of L. (Euphorbiaceae).

Convulsion is a typical symptom associated with epilepsy. , a common plant in Ghana, has been used traditionally for the management of epilepsy. This study was carried out to ascertain the scientific basis for the traditional utility of for various convulsive disorders and also determine the part of the plant with the most anticonvulsant activity.

Factors Influencing Adherence to Tuberculosis Treatment in the Ketu North District of the Volta Region, Ghana.

Annually, ten million cases of tuberculosis (TB) and about 1.8 million mortalities are recorded. Adherence to TB treatment not only reduces death outcomes but prevents prolonged sickness, transmission to others, and the development of multidrug-resistant TB.

Predicting type 2 diabetes mellitus among fishermen in Cape Coast: a comparison between the FINDRISC score and the metabolic syndrome.

Background: Studies over the past decades have observed a sharp rise in the prevalence and incidence of type 2 diabetes mellitus (T2DM). A highly sensitive and specific predictive tool for risky populations is essential. This study assessed two significant diabetes mellitus predictive tools for effectiveness and accuracy among people living in fishing communities in Cape Coast, Ghana.

Inter-rater Variability in Malaria Microscopy at the LEKMA Hospital, Ghana.

Background: Malaria remains a major cause of morbidity and mortality worldwide and particularly in sub-Saharan Africa where it is endemic. As such, it is important that a proper diagnosis is made before treatment is initiated. Malaria parasite count plays a key role in the diagnosis and management of malaria.

The Epidemiology of Bloodstream Infections and Antimicrobial Susceptibility Patterns: A Nine-Year Retrospective Study at St. Dominic Hospital, Akwatia, Ghana.

Background: Bloodstream infections are among the top causes of morbidity and mortality in people of all ages, especially in immunocompromised patients in sub-Saharan Africa. This study aimed at describing the epidemiology of bloodstream infections and antimicrobial susceptibility pattern over a nine-year period at St. Dominic Hospital, Akwatia, in the Eastern Region of Ghana.