[Epiphysiolysis of the medial clavicle with posterior dislocation : Video article].

Objective Of Surgery: The goal of surgery is the anatomical reduction and stable internal fixation of an epiphysiolysis of the medial clavicle with posterior luxation in a child without harming intrathoracic structures.

Indications: This case describes an acute epiphysiolysis of the medial clavicle Aitken type 0 with posterior dislocation.

Contraindications: Soft tissue infections within the region of the surgical access.

Habitat openness and predator abundance determine predation risk of warningly colored longhorn beetles (Cerambycidae) in temperate forest.

Organisms have evolved different defense mechanisms, such as crypsis and mimicry, to avoid detection and recognition by predators. A prominent example is Batesian mimicry, where palatable species mimic unpalatable or toxic ones, such as Clytini (Coleoptera: Cerambycidae) that mimic wasps. However, scientific evidence for the effectiveness of Batesian mimicry in Cerambycids in natural habitats is scarce.

Comparing the Toxicological Responses of Pulmonary Air-Liquid Interface Models upon Exposure to Differentially Treated Carbon Fibers.

In recent years, the use of carbon fibers (CFs) in various sectors of industry has been increasing. Despite the similarity of CF degradation products to other toxicologically relevant materials such as asbestos fibers and carbon nanotubes, a detailed toxicological evaluation of this class of material has yet to be performed. In this work, we exposed advanced air-liquid interface cell culture models of the human lung to CF.

Split-Ring Resonator Based Sensor for the Detection of Amino Acids in Liquids.

Amino acids belong to the most important compounds for life. They are structural components of proteins and required for growth and maintenance of cells. Essential amino acids cannot be produced by the organism and must be ingested through the nutrition.

[Development of specific guidance for the safe opening and operation of recreational destinations under pandemic conditions].

Background: The SARS-CoV‑2 pandemic led to the closure of leisure and recreation facilities worldwide. As part of a model study funded by the Baden-Wuerttemberg Ministry of Social Affairs, Health and Integration, it was possible to demonstrate how a hygiene and safety concept can be successfully implemented in practice using the example of the opening and operation of an amusement park in Baden-Wuerttemberg (Germany) under scientific supervision.

Objective: The aim of the model project was, besides the verification of a possible infection event through a visit to the amusement park, to develop and review a recommended course of action for the safe opening and operation of leisure facilities under pandemic conditions, which can be transferred to other destinations.

Aerosol measurement identifies SARS-CoV 2 PCR positive adults compared with healthy controls.

Background: SARS-CoV-2 is spread primarily through droplets and aerosols. Exhaled aerosols are generated in the upper airways through shear stress and in the lung periphery by 'reopening of collapsed airways'. Aerosol measuring may detect highly contagious individuals ("super spreaders or super-emitters") and discriminate between SARS-CoV-2 infected and non-infected individuals.

Evaluation of Real-world Data for Breast-MRI BI-RADS IV Lesions.

Background/aim: Magnetic resonance imaging (MRI) is an important diagnostic tool in the detection of breast cancer. The Breast Center of the municipal Hospital Holweide, Cologne, annually cares for and treats patients with changes in the breast. A special problem is posed by Breast Imaging-Reporting and Data System (BI-RADS) 4 lesions.

Exhaled Aerosols in SARS-CoV-2 Polymerase Chain Reaction-Positive Children and Age-Matched-Negative Controls.

Background: Children and adolescents seem to be less affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease in terms of severity, especially until the increasing spread of the omicron variant in December 2021. Anatomical structures and lower number of exhaled aerosols may in part explain this phenomenon. In a cohort of healthy and SARS-CoV-2 infected children, we compared exhaled particle counts to gain further insights about the spreading of SARS-CoV-2.

Bayesian logistic regression for online recalibration and revision of risk prediction models with performance guarantees.

Objective: After deploying a clinical prediction model, subsequently collected data can be used to fine-tune its predictions and adapt to temporal shifts. Because model updating carries risks of over-updating/fitting, we study online methods with performance guarantees.

Materials And Methods: We introduce 2 procedures for continual recalibration or revision of an underlying prediction model: Bayesian logistic regression (BLR) and a Markov variant that explicitly models distribution shifts (MarBLR).

Sarcoidosis involvement of the diaphragm leading to right diaphragmatic elevation: a case report.

A 69-year-old male Caucasian presenting with dyspnea on exertion related to unilateral diaphragmatic dysfunction as caused by sarcoidosis is described. First, right diaphragmatic elevation was unexplained, while the patient presented with a restrictive pattern in lung function testing using bodyplethysmography and with reduced global and diaphragmatic respiratory muscle strength as evidenced by respiratory pressures. Subsequently, surgical diaphragm plication was performed, unfortunately, without any clinical improvement.

Multimodal Sparse Classifier for Adolescent Brain Age Prediction.

The study of healthy brain development helps to better understand both brain transformation and connectivity patterns, which happen during childhood to adulthood. This study presents a sparse machine learning solution across whole-brain functional connectivity measures of three datasets, derived from resting state functional magnetic resonance imaging (rs-fMRI) and two task fMRI data including a working memory n-back task (nb-fMRI) and an emotion identification task (em-fMRI). The fMRI data are collected from the Philadelphia Neurodevelopmental Cohort (PNC) for the prediction of brain age in adolescents.

Group SLOPE - adaptive selection of groups of predictors.

Sorted L-One Penalized Estimation (SLOPE, Bogdan et al., 2013, 2015) is a relatively new convex optimization procedure which allows for adaptive selection of regressors under sparse high dimensional designs. Here we extend the idea of SLOPE to deal with the situation when one aims at selecting whole groups of explanatory variables instead of single regressors.

FDR-Corrected Sparse Canonical Correlation Analysis With Applications to Imaging Genomics.

Reducing the number of false discoveries is presently one of the most pressing issues in the life sciences. It is of especially great importance for many applications in neuroimaging and genomics, where data sets are typically high-dimensional, which means that the number of explanatory variables exceeds the sample size. The false discovery rate (FDR) is a criterion that can be employed to address that issue.

A Sparse Regression Method for Group-Wise Feature Selection with False Discovery Rate Control.

The method of Sorted L-One Penalized Estimation, or SLOPE, is a sparse regression method recently introduced by Bogdan et. al. [1] .

Pneumocystis jirovecii-induced chronic interstitial lung disease in Waldenström's macroglobulinemia.

Infections with Pneumocystis jirovecii can result in asymptomatic colonization or induce life threatening clinical symptoms. However, there appears to be a 'gray area' between colonization and severe pneumonia that remains underestimated so far. We describe a case with chronic interstitial lung disease and chronic cough that was attributed to P.

Intensity-based 2D 3D registration for lead localization in robot guided deep brain stimulation.

Intraoperative assessment of lead localization has become a standard procedure during deep brain stimulation surgery in many centers, allowing immediate verification of targeting accuracy and, if necessary, adjustment of the trajectory. The most suitable imaging modality to determine lead positioning, however, remains controversially discussed. Current approaches entail the implementation of computed tomography and magnetic resonance imaging.

Differential effects of film on preschool children's behaviour dependent on editing pace.

Aim: Evidence on how the pace of television and film editing affects children's behaviour and attention is inconclusive. We examined whether a fast-paced film affected how preschool-aged children interacted with toys.

Methods: The study comprised 70 children (36 girls) aged two to four-and-a-half years who attended preschools in Essex, United Kingdom.

Unified tests for fine-scale mapping and identifying sparse high-dimensional sequence associations.

Motivation: In searching for genetic variants for complex diseases with deep sequencing data, genomic marker sets of high-dimensional genotypic data and sparse functional variants are quite common. Existing sequence association tests are incapable of identifying such marker sets or individual causal loci, although they appeared powerful to identify small marker sets with dense functional variants. In sequence association studies of admixed individuals, cryptic relatedness and population structure are known to confound the association analyses.

Hyperbaric Oxygen Promotes Proximal Bone Regeneration and Organized Collagen Composition during Digit Regeneration.

Oxygen is critical for optimal bone regeneration. While axolotls and salamanders have retained the ability to regenerate whole limbs, mammalian regeneration is restricted to the distal tip of the digit (P3) in mice, primates, and humans. Our previous study revealed the oxygen microenvironment during regeneration is dynamic and temporally influential in building and degrading bone.

Massive cerebral air embolism after blunt chest trauma with full neurological recovery.

Cerebral air embolism (CAE) is a common, often lethal, complication in blunt and penetrating chest trauma. The factors affecting the outcome of CAE patients are poorly understood, and there is no generally accepted treatment algorithm. In this report, we present the case of a 28-year-old male motorcyclist with a massive CAE, including bilateral internal carotid artery air on computed tomographic examination following blunt chest trauma.

[Unilateral agenesis of pulmonal artery in adults: a rare disease frequently undiagnosed].

Introduction: Unilateral absence of a pulmonary artery (UAPA) in adults without any other cardiovascular anomalies is a very rare clinical entity. Usually UAPA in adults remains undetected because of the symptom-free clinical course. The most common symptoms are hemoptysis and recurrent pulmonary infections.