Features of Myocarditis: Morphological Differential Diagnosis in Post-COVID-19 Children.

Unlabelled: Myocarditis is characterized by dysfunction and destruction of cardiomyocytes, infiltrative inflammation, and development of fibrosis. Late diagnosis of myocarditis has been a serious global health problem, especially due to the spread of a new coronavirus infection. The aim of this review is to identify differences between myocarditis of viral etiology, including SARS-CoV-2 lesions, based on instrumental and pathomorphological findings.

Circulating Regulatory T Cell Subsets in Patients with Sarcoidosis.

Unlabelled: Over recent years, many researchers have supported the autoimmune theory of sarcoidosis. The presence of uncontrolled inflammatory response on local and system levels in patients with sarcoidosis did not define that the immunoregulatory mechanisms could be affected. The aim of this study was to evaluate the distribution and the disturbance circulating Treg cell subsets in the peripheral blood in patients with sarcoidosis.

Severe Course of COVID-19 and Long-COVID-19 in Children: Difficulties in Diagnosis.

The question of COVID-19 and long-COVID-19 course in children remains unsolved. This infection in children, which is associated with COVID-19, can vary from asymptomatic to systemic damage of various systems. Multisystem inflammatory syndrome in children, associated with SARS-CoV-2 (MIS-C), is a serious condition in children and adolescents after experiencing COVID-19.

Identification of autoimmune markers in pulmonary tuberculosis.

Introduction: Pathogenesis of many autoimmune diseases is mainly promoted by poorly regulated and/or wrong targeted immune response to pathogens including . Autoimmunity is one of the processes with are characteristics of tuberculosis (Tbc). The aim was to determine the autoimmune clinical and immunological features in patients with pulmonary Tbc.

COVID-19 Heart Lesions in Children: Clinical, Diagnostic and Immunological Changes.

In the beginning of COVID-19, the proportion of confirmed cases in the pediatric population was relatively small and there was an opinion that children often had a mild or asymptomatic course of infection. Our understanding of the immune response, diagnosis and treatment of COVID-19 is highly oriented towards the adult population. At the same time, despite the fact that COVID-19 in children usually occurs in a mild form, there is an incomplete understanding of the course as an acute infection and its subsequent manifestations such as Long-COVID-19 or Post-COVID-19, PASC in the pediatric population, correlations with comorbidities and immunological changes.

Cardiac Involvement in Children Affected by COVID-19: Clinical Features and Diagnosis.

COVID-19 () in children is usually mild. However, multiple organ disorders associated with SARS-CoV-2 () have been detected with poor respiratory symptoms. Cardiac changes are noted in 17% to 75% of cases, which are associated with diagnostic difficulties in high-risk groups for the development of complications that are associated with myocardial damage by the SARS-CoV-2 virus.

Efficacy of Tuberculosis Treatment in Patients with Drug-Resistant Tuberculosis with the Use of Bedaquiline: The Experience of the Russian Federation.

Unlabelled: In the conditions of the continued growth of multiple- and extensive drug-resistant tuberculosis, use of the new highly effective anti-tuberculosis drugs in this patient category is of great relevance. The aim of the study was determination the efficacy of treatment in patients with multidrug- and extensive drug-resistant tuberculosis using bedaquiline based on studies published in the Russian Federation.

Materials And Methods: The authors analyzed data published in studies from 2014 to 2022; 41 publications were included in total and 17 articles corresponded to the study design.

Tuberculosis in the Russian Federation: Dynamics of the Epidemic Indicators before and after COVID-19 Pandemic.

The measures taken against tuberculosis (TB) in recent years in the Russian Federation have been highly effective. Unfortunately, the COVID-19 pandemic may seriously undermine the progress that has been made in the fight against TB. The aim of this study was to assess changes in the epidemiological rates of tuberculosis in the Russian Federation before and after the COVID-19 pandemic.

Sarcoidosis: Progression to the chronic stage and pathogenic based treatment (narrative review).

Many factors confirm the autoimmune nature of sarcoidosis and help in determining the strategy of patient management and treatment initiation. However, the causes and the mechanisms of disease progression that result in fibrosis and insufficiency of the affected organ remain unclear. This narrative review aims to analyse the mechanisms and biomarkers of sarcoidosis progression, as well as the pathogenetic basis of sarcoidosis therapy.

Molecular and Cellular Mechanisms of and SARS-CoV-2 Infections-Unexpected Similarities of Pathogenesis and What to Expect from Co-Infection.

Tuberculosis is still an important medical and social problem. In recent years, great strides have been made in the fight against , especially in the Russian Federation. However, the emergence of a new coronavirus infection (COVID-19) has led to the long-term isolation of the population on the one hand and to the relevance of using personal protective equipment on the other.

Post COVID-19 Syndrome in Patients with Asymptomatic/Mild Form.

Post COVID-19 Syndrome (PCS) is a complex of various symptoms developing a month or more after the acute phase of the disease. The cases of PCS development among patients with asymptomatic/mild forms are frequently reported; however, the pathogenesis of PCS in this group of patients is still not completely clear. The publications about COVID-19 which were published in online databases from December 2019 to September 2021 are analyzed in this review.

Efficacy of Different Types of Therapy for COVID-19: A Comprehensive Review.

A new coronavirus disease (COVID-19) has already affected millions of people in 213 countries. The possibilities of treatment have been reviewed in recent publications but there are many controversial results and conclusions. An analysis of the studies did not reveal a difference in mortality level between people treated with standard therapy, such as antiviral drugs and dexamethasone, and new antiviral drugs/additional immune therapy.

Stochastic-Biomechanic Modeling and Recognition of Human Movement Primitives, in Industry, Using Wearables.

In industry, ergonomists apply heuristic methods to determine workers' exposure to ergonomic risks; however, current methods are limited to evaluating postures or measuring the duration and frequency of professional tasks. The work described here aims to deepen ergonomic analysis by using joint angles computed from inertial sensors to model the dynamics of professional movements and the collaboration between joints. This work is based on the hypothesis that with these models, it is possible to forecast workers' posture and identify the joints contributing to the motion, which can later be used for ergonomic risk prevention.

Ultrasensitive 3D Aerosol-Jet-Printed Perovskite X-ray Photodetector.

X-ray photon detection is important for a wide range of applications. The highest demand, however, comes from medical imaging, which requires cost-effective, high-resolution detectors operating at low-photon flux, therefore stimulating the search for novel materials and new approaches. Recently, hybrid halide perovskite CHNHPbI (MAPbI) has attracted considerable attention due to its advantageous optoelectronic properties and low fabrication costs.

Human Movement Representation on Multivariate Time Series for Recognition of Professional Gestures and Forecasting Their Trajectories.

Human-centered artificial intelligence is increasingly deployed in professional workplaces in Industry 4.0 to address various challenges related to the collaboration between the operators and the machines, the augmentation of their capabilities, or the improvement of the quality of their work and life in general. Intelligent systems and autonomous machines need to continuously recognize and follow the professional actions and gestures of the operators in order to collaborate with them and anticipate their trajectories for avoiding potential collisions and accidents.

Pressure-induced transformation of CHNHPbI: the role of the noble-gas pressure transmitting media.

The photovoltaic perovskite, methylammonium lead triiodide [CHNHPbI (MAPbI)], is one of the most efficient materials for solar energy conversion. Various kinds of chemical and physical modifications have been applied to MAPbI towards better understanding of the relation between composition, structure, electronic properties and energy conversion efficiency of this material. Pressure is a particularly useful tool, as it can substantially reduce the interatomic spacing in this relatively soft material and cause significant modifications to the electronic structure.

Large-Size Single-Crystal Oligothiophene-Based Monolayers for Field-Effect Transistors.

High structural quality of crystalline organic semiconductors is the basis of their superior electrical performance. Recent progress in quasi two-dimensional (2D) organic semiconductor films challenges bulk single crystals because both demonstrate competing charge-carrier mobilities. As the thinnest molecular semiconductors, monolayers offer numerous advantages such as unmatched flexibility and light transparency as well  they are an excellent platform for sensing.

[Study of photodynamic treatment for P-388 lympho-leukemia in mice].

Data are presented on the results of photodynamic treatment (PDT) of mice DBA2 with transplantable lympho-leukemia P-388. Different regimens of photosensitizer Dimegin and emission were used. Both intravenous PDT and in combination with local PDT should be recommended.

[The manifestations of toxicity of nanoparticles (a review)].

The analysis of the data available in the literature has shown that nanoparticles (NP) have a high toxicity than usual microparticles, can penetrate unchanged across the cell barriers, the blood-brain barrier into the central nervous system, circulate and accumulate in the organs and tissues, by inducing more significant pathomorphological lesions in the visceral organs, and have a long elimination half-life. The toxicity of HPs is determined by their shape and sizes; moreover, minute fusiform particles cause more destructive effects than similar spherical particles; upon exposure, there is a clear dose-effect relationship. According to exposure to NPs, the classical target organs for the latter are the lung, liver, kidney, brain, gastrointestinal tract.

Prevalence and correlates of asthma among children in central St. Petersburg, Russia: cross-sectional study.

Aim: To estimate the prevalence of asthma among children in central St. Petersburg and to evaluate associations between asthma and socio-demographic, biological, and environmental factors.

Methods: A cross-sectional study included 1464 children aged 0-18 years from two central districts of St.

[Biological effects of Lamipharen photodynamic therapy].

Biological effects of Lamipharen treatment of sarcoma M-1 was studied in newborn rats and photodynamic therapy in combination with radiation was evaluated.