Parry-Romberg syndrome is a hemifacial atrophy which can be complicated by melasma. We present two cases of Parry-Romberg syndrome, treated by fat transfer and bleaching of the skin using a modified "Kligman's formula." The atrophy, as well as the skin dyschromia, improved, and the results were stable.
View Article and Find Full Text PDFDNA methylation is the best characterised epigenetic change so far. However, its role in breast cancer metastasis has not as yet been elucidated. The aim of this study was to investigate the differences between the methylation profiles characterising primary tumours and their corresponding positive or negative for metastasis lymph nodes (LN) and correlate these with tumour metastatic potential.
View Article and Find Full Text PDFCalcification remains the main reason for failure of bioprosthetic valves. The aim of this study was to evaluate the in vivo calcification response of a new bioprosthetic valve, derived from cardiac tissue of Phoca groenlandica. Aortic and pulmonary leaflets, bovine, and Phoca groenlandica pericardia were fixed in buffered glutaraldehyde solution.
View Article and Find Full Text PDFA 65-year-old woman presented with abdominal pain, weight loss, fatigue, and microcytic anemia. Esophagogastroduodenoscopy, until the second part of duodenum, was normal. Ultrasound and computed tomography demonstrated a solid mass in the distal duodenum.
View Article and Find Full Text PDFApoptosis has been suggested to have an important role in the pathogenesis of restenosis in addition to cell migration and proliferation. The aim of the present study was to investigate in an experimental in vivo model the occurrence of apoptosis postangioplasty and its relation to bcl-2 and peroxynitrite detection. Eighteen hypercholesterolemic rabbits underwent transluminal angioplasty of the right iliac artery.
View Article and Find Full Text PDFBackground: Our purpose was to investigate the expression of FHIT (Fragile Histidine Triad) gene product in a series of 110 urinary bladder TCCs, and its eventual relationship with histological grade, clinical stage, recurrences and patients' survival.
Materials And Methods: We performed immunohistochemistry in archival material of formalin-fixed, paraffin-embedded tissues, using the anti-Fhit antibody and the Streptavidin-biotin peroxidase method.
Results: In 30 out of 110 cases (27.