Publications by authors named "Gloriana Barrientos"

Purpose: The RESPIRA cohort aims to describe the nature, magnitude, time course and efficacy of the immune response to SARS-CoV-2 infection and vaccination, population prevalence, and household transmission of COVID-19.

Participants: From November 2020, we selected age-stratified random samples of COVID-19 cases from Costa Rica confirmed by PCR. For each case, two population-based controls, matched on age, sex and census tract were recruited, supplemented with hospitalised cases and household contacts.

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Objetivo: Estimar la prevalencia e identificar determinantes de la infección por el virus del papiloma humano (VPH) en mujeres jóvenes (18-25 años). Material y métodos. Se analizaron datos de 5 871 mujeres sexualmente activas a quienes se les realizó una entrevista y toma de muestras cervicouterinas para detección de VPH y citología durante la visita de reclutamiento del Ensayo de Vacunación contra VPH16/18 en Costa Rica.

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Article Synopsis
  • HPV vaccination is crucial for preventing cervical cancer in adolescent girls, but many are under-vaccinated due to cost and logistics.
  • Research indicates that a single dose of the HPV vaccine may be as effective as two doses, which led to a large trial comparing the effectiveness of one versus two doses of bivalent and nonavalent vaccines.
  • The ESCUDDO trial, involving over 20,000 girls in Costa Rica, aims to evaluate vaccine efficacy through follow-up visits and comparisons with unvaccinated women.
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