Publications by authors named "Gloria O Izu"
Article Synopsis
- The study explores the effects of litchi peel ethyl acetate extract on diabetes-related issues in a rat model, focusing on its flavonoid profile and potential glycemic control.
- The extract showed significant improvement in glucose tolerance and pancreatic health compared to untreated diabetic rats, comparable to the effects of metformin.
- Key flavonoids identified in the extract may contribute to enhancing glycogen storage and insulin signaling, suggesting its potential as a natural remedy for diabetes management and oxidative stress reduction.
Bioactive flavonoid epicatechin has been reported in the peel of litchi fruit but isolated from its hydroalcoholic extracts. This study isolated epicatechin with cellular glucose uptake modulatory and ROS production inhibitory properties from the ethyl acetate (EtOAc) extract using a bioassay-guided approach. The fruit peel was defatted with hexane and sequentially extracted using dichloromethane (DCM), EtOAc, methanol (MeOH) and water.
View Article and Find Full Text PDFOxidative stress is pivotal in the pathology of many diseases. This study investigated the antioxidant phytochemistry of avocado ( Mill.) peel.
View Article and Find Full Text PDFThe perception that many fruit wastes, particularly the peel, contain more phytochemicals than the edible portions has been largely supported by scientific evidence, making them potential sources of bioactive and therapeutic phytochemicals. The peel and seed of Litchi (Litchi chinensis Sonn.) contain bioactive principles and have been shown to exhibit antioxidative, antidiabetic, cancer preventive, anti-obesogenic, and anti-inflammatory properties.
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