Publications by authors named "Gloria Mateo"
Article Synopsis
- Alzheimer's disease is a significant health issue for older adults with Down syndrome, and typical diagnostic methods, like MRI, are often not suitable due to difficulties with prolonged scan times.
- This study used automated analysis of CT scans from 98 individuals with Down syndrome to identify correlations between brain structure changes and the severity of dementia stages, alongside specific Alzheimer’s biomarkers.
- The findings indicated that increased dementia severity was linked to reduced gray and white matter volumes in the temporal lobe, suggesting a promising new method for assessing Alzheimer’s in populations that struggle with traditional imaging techniques.
Thrombospondin-1 is a matricellular protein with potent antitumour activities, the levels of which determine the fate of many different tumours, including renal carcinomas. However, the factors that regulate this protein remain unclear. In renal carcinomas, hypoxic conditions enhance the expression of angiogenic factors that help adapt tumour cells to their hostile environment.
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