Metabolic abnormalities and polymorphisms of the vitamin D receptor (VDR) and ZNF365 genes in children with urolithiasis.

Composition of urinary stones in children from Yucatán, México, is calcium and uric acid. Polymorphisms in VDR and ZNF365 genes have been associated to calcium and uric acid lithiasis, respectively. We evaluated the association of polymorphisms TaqI and FokI of VDR gene and Ala62Thr of ZNF365 gene with the metabolic disorders (MD) in children with urolithiasis (UL).

[Nephrolithiasis as a nephrectomy surgical indication. A multicentric study].

Background: urolithiasis is endemic in Yucatan, Mexico, and its complications are abscesses and renal exclusion which end up in a nephrectomy. Our objective in this paper was to know the nephrectomy indications in Yucatecan population.

Methods: the nephrectomies from four concentrations hospitals of the Health Services, were analyzed.

[Four years experience in the follow up of nursing children with urolithiasis].

Objective: to describe clinical data, metabolic profile, treatment and evolution of a nursing children cohort with urolithiasis.

Methods: using a descriptive, prospective and longitudinal design, were registered all patients with urolithiasis, of Pediatric Division at the Hospital General "Agustín O'Horán," in Yucatan, Mexico. We included all patients who were 36 months old and younger.