Significant association between and gene polymorphisms and chronic spontaneous urticaria in a Colombian Caribbean population.

Introduction: Chronic spontaneous urticaria (CSU) is an inflammatory skin disease related to poor quality of life. Previous studies have found that vitamin D deficiency and vitamin D receptor () , and gene single-nucleotide polymorphisms (SNPs) influence immune response and susceptibility to skin disorders.

Aim: To explore the role of SNPs, and the association of vitamin D serum levels in a sample of Colombian Caribbean CSU patients.

Multicentric and Observational Study of Omalizumab for Chronic Spontaneous Urticaria in Real-Life in Colombia.

Background: Although chronic urticaria (CU) is a common, cause of medical consulting both in general practitioners and allergist specialists worldwide, there is little information about its behavior and management in Latin America. Currently, national and international guidelines recommend using Omalizumab for cases refractory to management with antihistamines. Despite advances in the knowledge of Omalizumab for the management of CU, although there are few studies in underdeveloped countries, there are many studies evaluating the impact of Omalizumab treatment.