Publications by authors named "Gloria Candelas-Rodriguez"

: Emerging evidence suggests that SARS-CoV-2 infection and vaccines may trigger autoimmune responses in predisposed individuals. Idiopathic inflammatory myopathies (IIMs) are diseases with diverse clinical manifestations, often associated with myositis autoantibodies (MAs). Diagnosing IIM is challenging due to limitations in classification criteria and diagnostic assays.

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Objective: To present recommendations based on the available evidence and the consensus of experts, for risk management of biological treatment and JAK inhibitors in patients with rheumatoid arthritis.

Methods: Clinical research questions relevant to the purpose of the document were identified. These questions were reformulated in PICO format (patient, intervention, comparison, outcome or outcome) by a panel of experts, selected based on their experience in the area.

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Article Synopsis
  • A study examined the immune response to the third dose of anti-SARS-CoV-2 vaccines in patients with immune-mediated rheumatic diseases (IMRDs) who are undergoing different immunosuppressive treatments.
  • Involvement included 79 IMRD patients and 31 healthy controls (HC), measuring cytokine production and antibody levels post-vaccination.
  • Results indicated that while most IMRD patients had immune responses, those on methotrexate and leflunomide had lower antibody and T-cell responses compared to healthy controls, suggesting some treatments may hinder vaccine efficacy.
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Objective: To update the recommendations on osteoporosis (OP) of the Spanish Society of Rheumatology (SER) based on the best possible evidence.

Methods: A panel of nine expert rheumatologists in OP was created, previously selected by the SER through an open call. The phases of the work were: identification of the key areas for updating the previous consensus, analysis and synthesis of the scientific evidence (using the SIGN levels of evidence) and formulation of recommendations based on this evidence and consensus techniques.

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Objectives: To evaluate the association between smoking and clinical parameters and structural damage in axial spondyloarthritis (axSpA).

Methods: We systematically searched MEDLINE, EMBASE and Cochrane Library till November 2015. We selected articles that analysed the smoking impact on disease activity, functional status, structural damage, physical mobility and life quality.

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