Pericarditis following permanent pacemaker insertion.

Background: The appearance of pericarditis following insertion of a permanent pacemaker is not widely acknowledged in the literature.

Objectives: To describe our experience with pericarditis following 395 permanent pacemaker implantations over 2 years.

Methods: We retrospectively reviewed the medical records of 395 consecutive patients in whom new pacing systems or pacemaker leads had been implanted over a 2 year period.

Clinical characteristics of unexpected death among young enlisted military personnel: results of a three-decade retrospective surveillance.

Study Objective: To explore the causes of sudden and unexpected death in a young and healthy military population, to examine the various patterns of diseases associated with these tragic events, and to investigate the factors found to be associated with this grave outcome.

Design: We retrospectively investigated 151 cases of Israeli military personnel who died unexpectedly over a 30-year period. We collected all the available medical records, autopsy results, and investigation committee reports.

Long-term outcome of patients who received implantable cardioverter defibrillators for stable ventricular tachycardia.

Introduction: Evidence is inconclusive concerning the role of implantable cardioverter defibrillators (ICDs) to treat patients with hemodynamically stable ventricular tachycardia (VT). The goal of this study was to estimate future risk of unstable ventricular arrhythmias in patients who received ICDs for stable VT.

Methods And Results: We reviewed complete ICD follow-up data from 82 patients (age 66.

Use of automatic threshold tracking function with non-low polarization leads: risk for algorithm malfunction.

The AutoCapture (AC) function of new pacemakers (PM) from St Jude Medical (SJM) was originally recommended for use with low polarization (LP) ventricular leads only.However, recent reports have encouraged the use of the AC function with various leads, including those lacking a special LP design. The objective of this study was to analyze the reliability and safety of the AC algorithm application with different types of pacing leads.

Long-term prognosis of inducible ventricular flutter: not an innocent finding.

Background: The prognostic significance of ventricular flutter (VFL) induced during programmed electrical stimulation (PES) is currently unknown.

Methods: This study examined patients who had PES-induced VFL and assessed their long-term prognosis compared with patients who had inducible sustained monomorphic ventricular tachycardia (SMVT).

Results: Of 3414 patients undergoing PES, 74 (2%) had sustained VFL.

A novel form of familial bidirectional ventricular tachycardia.

We evaluated a family with 30 members, 3 of whom had incessant polymorphous and bidirectional ventricular tachycardia (VT) that was electrocardiographically similar to that described in other familial polymorphic VT series; the VT was unrelated to exercise and asymptomatic. More subtle, but morphologically similar, ventricular arrhythmias were detected in 3 other family members. Genes related to intracellular calcium transport were specifically excluded.

Managing pacemaker safety alerts: experience with three successive models of a single manufacturer.

This report describes the experience of a large pacemaker center during three successive replacement operations due to safety alerts involving three models from the same manufacturer. Between March 1993 and May 1999, 210 patients were implanted with three DDD pacemaker models (Sorin Biomedica, Saluggia, Italy) that were subsequently subject to safety alerts. Pacemaker records were reviewed for complications related to device malfunction, and those secondary to the replacement procedure.

Discrepancies between the upper limit of vulnerability and defibrillation threshold: prevalence and clinical predictors.

Introduction: Upper limit of vulnerability (ULV) has a strong correlation with defibrillation threshold (DFT) in patients with implantable cardioverter defibrillators (ICDs). Significant discrepancies between ULV and DFT are infrequent. The aim of this study was to characterize patients with such discrepancies.

Cardiac resynchronization therapy: a new frontier in the management of heart failure.

CRT offers today another option for some patients with heart failure, side by side with more "traditional" therapies like drugs, assist devices, and heart transplantation. Clinical studies show that in properly selected patients a significant improvement in hemodynamic parameters and clinical status can be achieved by BV pacing. It is still unknown whether this type of therapy will also result in a survival benefit for patients with severe heart failure.

ST-segment deviation following implantable cardioverter defibrillator shocks: incidence, timing, and clinical significance.

ST-segment analysis is frequently used during surgical procedures, while ST deviation is considered a sign of myocardial injury. ST deviations were reported following transthoracic and epicardial electrical shocks. The prevalence, timing, and clinical significance of ST-segment deviation following endocardial ICD shocks are discussed in this article.

Multiple pulse generator malfunctions with a dual chamber pacemaker.

The aim of this study was to evaluate the dual chamber uni/bipolarpacemaker Minidual 50, manufactured by Sorin Biomedica. Between 1995 and 1998, 66 Minidual 50 models were implanted at the Heart Institute. During the follow-up period of 33 +/- 12.

Noncontact mapping to guide ablation of right ventricular outflow tract tachycardia.

Objectives: [corrected] The aim of this study was to determine whether noncontact mapping is feasible in the right ventricle and assess its utility in guiding ablation of difficult-to-treat right ventricular outflow tract (RVOT) ventricular tachycardia (VT).

Background: In patients without inducible arrhythmia, RVOT VT may be difficult to ablate. Noncontact mapping permits ablation guided by a single tachycardia complex, which may facilitate ablation of difficult cases.

Impaired detection of ventricular tachyarrhythmias by a rate-smoothing algorithm in dual-chamber implantable defibrillators: intradevice interactions.

Introduction: Rate smoothing is an algorithm initially designed to prevent rapid changes in pacemaker rates. In this study, we sought to determine the potential of the rate-smoothing mechanism in preventing detection of ventricular tachyarrhythmias.

Methods And Results: Clinical testing of rate smoothing was performed at the time of defibrillator arrhythmia induction in 16 patients with implantable defibrillators during 65 episodes of ventricular tachyarrhythmias.

Inhibition of biventricular pacemakers by oversensing of far-field atrial depolarization.

This report describes two patients who exhibited far-field oversensing of the P wave by the ventricular channel of a DDD biventricular pacemaker implanted for the treatment of congestive heart failure. Oversensing probably occurred secondary to slight displacement of the left ventricular lead in the coronary venous system. Long-term reliable pacing was restored by decreasing the sensitivity of the ventricular channel.

The adenosine triphosphate test: a bedside diagnostic tool for identifying the mechanism of supraventricular tachycardia in patients with palpitations.

Objectives: This study assesses the value of the "ATP test" (injection of adenosine triphosphate [ATP] during sinus rhythm) for identifying patients with palpitations of unclear etiology who actually have atrioventricular (AV) nodal re-entry tachycardia (AVNRT) or AV re-entry tachycardia (AVRT).

Background: Because AVNRT and AVRT can be cured with radiofrequency ablation, documentation of spontaneous AVNRT or AVRT usually prompts referral for electrophysiologic (EP) evaluation. However, these paroxysmal arrhythmias may elude clinical diagnosis.

The implantable cardioverter defibrillator.

Implantable cardioverter defibrillators (ICDs) have evolved from the treatment of last resort to the gold standard therapy for patients at high risk for ventricular tachyarrhythmias. High-risk patients include those who have survived life-threatening arrhythmias, and individuals with cardiac diseases who are at risk for such arrhythmias, but are symptomless. Use of an ICD will affect the patient's quality of life.

Cardiac pacing. A review.

Pacing is a field of rapid clinical progress and technologic advances. Clinical progress in the 1990s included the refinement of indications for pacing as well as the use of pacemakers for new, nonbradycardiac indications, such as the treatment of cardiomyopathies and CHF and the prevention of atrial fibrillation. Important published data and studies in progress are shedding new light on issues of pacing mode selection, and they may influence future practice significantly.

Randomized comparison of J-shaped and straight atrial screw-in pacing leads.

Objective: To study the importance of a J shape in atrial pacing leads.

Patients And Methods: We compared in a randomized controlled study acute and chronic results with 2 steroid-eluting, polyurethane, screw-in atrial lead models that differ only in shape. A total of 208 patients were randomized to have implantation of either a straight atrial lead (n = 105) or a J-shaped atrial lead (n = 103).

Rate smoothing with cardiac pacing for preventing torsade de pointes.

Cardiac pacing remains one of the most effective means for preventing torsade de pointes in patients with long QT syndrome (LQTS). However, fatal arrhythmias may occur despite combined therapy with beta blockers and pacing, and it is possible that failure of cardiac pacing for preventing arrhythmias in the long run is related (at least in part) to suboptimal pacemaker programming. Preventing sudden pauses may be especially important for preventing arrhythmias in the LQTS because such pauses are highly proarrhythmic in this patient population.

Effect of implantable cardioverter-defibrillator shocks on QT dispersion.

Following transvenous implantable cardioverter defibrillator shocks, a significant increase in QT dispersion was observed. We suggest shock-induced increased dispersion of myocardial repolarization as one of the mechanisms of shock-induced proarrhythmia.

Adenosine-5'-triphosphate test for the noninvasive diagnosis of concealed accessory pathway.

Objectives: This study assessed the use of adenosine triphosphate (ATP) in the noninvasive diagnosis of concealed accessory pathway (AP) and dual atrioventricular (AV) node physiology in patients with inducible AV reentrant tachycardia (AVRT).

Background: Administration of ATP during sinus rhythm identifies dual AV node physiology in 76% of patients with inducible sustained slow/fast AV nodal reentry tachycardia (AVNRT).

Methods: Incremental doses of ATP were intravenously administered during sinus rhythm to 34 patients with inducible sustained AVRT involving a concealed AP and to 27 control patients without AP or dual AV node physiology.