A Prospective, Randomized, Double-blind, Placebo-controlled Study of Orbital Radiotherapy for Graves' Ophthalmopathy.

Context: Although widely used for more than 85 years, the efficacy of radiotherapy for Graves' ophthalmopathy (GO) has not been established convincingly.

Objective: To evaluate the efficacy of radiotherapy for GO.

Design: Prospective, randomized, internally controlled, double-blind clinical trial in a tertiary care academic medical center.

Retinal microvascular abnormalities in patients treated with external radiation for graves ophthalmopathy.

Background: A prospective study was conducted to determine if external ionizing radiation could favorably influence the orbital manifestations of Graves ophthalmopathy. Diabetes and untreated systemic hypertension were exclusion criteria. Radiation was directed to the orbits of 42 affected patients using 0.

The aftermath of orbital radiotherapy for graves' ophthalmopathy.

Objective: To determine whether long-term improvement could be observed after orbital radiotherapy for Graves' disease; in addition, to evaluate ancillary treatments needed for those who have received radiotherapy, to search for late-emerging adverse consequences of radiotherapy, and to relate orbital changes to serum levels of thyroid-stimulating immunoglobulin (TSI).

Design: Three-year follow-up of noncomparative interventional case series.

Participants: Forty-two patients.