Synopsis of recent research by authors named "Glenn McEnroe"
Glenn McEnroe's recent research predominantly focuses on the mechanisms of bacterial resistance and novel therapeutic strategies targeting transforming growth factor-beta (TGF-beta) signaling pathways in cancer.
His work includes identifying mutations in penicillin-binding proteins (PBPs) that decrease susceptibility to β-lactam antibiotics in Escherichia coli, revealing significant insights into antibiotic resistance.
Additionally, he has explored the synthesis of new tetracyclic fluoroquinolones with enhanced antibacterial potency and investigated the inhibition of TGF-beta signaling as a method to restore immune surveillance in glioma and pancreatic carcinoma models.