Actinic keratoses, basal cell carcinoma, and squamous cell carcinoma: uncommon treatments.

This contribution will discuss the treatment of actinic keratoses, basal cell carcinomas, and squamous cell carcinoma using methods that are not routinely established but have been used for a long period. The purpose of this article is simply to expand the reader's knowledge of what has been or could be used to treat such lesions. This article should not be interpreted as advocating the use of the methods discussed because there are obviously efficient well-established treatments for these lesions.

Polyarteritis nodosa and cutaneous polyarteritis nodosa.

Cutaneous vasculitis can present with a variety of lesions and associated symptoms. It is important for the clinician to be able to recognize vasculitis lesions and know when to pursue further laboratory studies that will determine the extent of the disease process in a patient. This review compares and contrasts polyarteritis nodosa with its cutaneous counterpart.

Necrobiotic xanthogranuloma with scleroderma.

I report the case of a 68-year-old man who presented with necrobiotic xanthogranuloma (NXG) with concomitant scleroderma, along with the presence of cryoglobulins and cryofibrinogen in the blood. Autoamputation of the distal fingers and parts of the ears also occurred, over time, with exposure to cold temperatures. This is an interesting constellation of findings in this rare disorder that raises questions concerning its pathogenesis.

Cutaneous manifestations of antiretroviral therapy.

The pandemic created by HIV, a retrovirus, has stimulated increased research in viral diseases and has generated greater interest in the development of antiretroviral medications. These new medications are presently divided into 3 categories: protease inhibitors (PIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), and nucleoside reverse transcriptase inhibitors (NRTIs). These antiretroviral agents carry their own risk for causing adverse reactions, as well as drug interactions.