A margin-of-the-day online adaptive intensity-modulated radiotherapy strategy for cervical cancer provides superior treatment accuracy compared to clinically recommended margins: a dosimetric evaluation.

Purpose: To dosimetrically evaluate a margin-of-the-day (MoD) online adaptive intensity-modulated radiotherapy (IMRT) strategy for cervical cancer patients. The strategy is based on a single planning computed tomography (CT) scan and a pretreatment constructed IMRT plan library with incremental clinical target volumes (CTV)-to-planning target volumes (PTV) margins.

Material And Methods: For 14 patients, 9-10 variable bladder filling CT scans acquired at pretreatment and after 40 Gy were available.

Toward an individualized target motion management for IMRT of cervical cancer based on model-predicted cervix-uterus shape and position.

Background And Purpose: To design and evaluate a 3D patient-specific model to predict the cervix-uterus shape and position.

Methods And Materials: For 13 patients lying in prone position, 10 variable bladder filling CT-scans were acquired, 5 at planning and 5 after 40Gy. The delineated cervix-uterus volumes in 2-5 pre-treatment CT-scans were used to generate patient-specific models that predict the cervix-uterus geometry by bladder volume.