Reducing Alcohol and Opioid Use Among Youth in Rural Counties: An Innovative Training Protocol for Primary Health Care Providers and School Personnel.

Background: Given that youth alcohol use is more common in rural communities, such communities can play a key role in preventing alcohol use among adolescents. Guidelines recommend primary care providers incorporate screening, brief intervention, and referral to treatment (SBIRT) into routine care.

Objective: The aim is to train primary care providers and school nurses within a rural 10-county catchment area in Pennsylvania to use SBIRT and facilitate collaboration with community organizations to better coordinate substance use prevention efforts.

Multi-model implementation of evidence-based care in the treatment of opioid use disorder in Pennsylvania.

Pennsylvania has the third highest rate of death due to drug overdose (44.3 per 100,000) in the country, which is significantly higher than the national rate. This continues to have drastic societal impact.

Intracranial salivary gland choristoma within optic nerve dural sheath: case report and review of the literature.

Objective: Salivary gland choristomas or their neoplastic derivatives may appear throughout the intracranial space, most frequently in the middle ear or sella. Here, we present the case of a salivary gland choristoma embedded within the optic nerve dural sheath and review the literature of intracranial salivary gland masses.

Case Presentation: A 28-year-old female patient presented with headache and visual complaints.

Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium.

The cyclin D1 oncogene is frequently amplified/overexpressed in oral squamous cell carcinomas. Mice with overexpression of cyclin D1 targeted to the stratified squamous epithelia of the tongue, esophagus, and forestomach develop a phenotype of epithelial dysplasia at these sites. In this study, we examined the effect of cyclin D1 overexpression on susceptibility of mice to carcinogen-induced tumorigenesis, using 4-nitroquinoline-1-oxide (4NQO), an established potent oral carcinogen in mice.

Effects of anesthetic agents on serum parathyroid hormone and calcium concentrations in mice.

Objective: To determine the effects of three anesthetic regimens on serum calcium and parathyroid hormone (PTH) in mice.

Study Design: Prospective experimental study.

Animals: Twenty-seven, 12-week-old, FVB mice.