Estrogen and skin: the effects of estrogen, menopause, and hormone replacement therapy on the skin.

Unlabelled: Aging is associated with declining levels of several hormones, including estrogen. Although the effects of estrogen on the skin are still not fully understood, it is known that, in women, declining estrogen levels are associated with a variety of cutaneous changes, many of which can be reversed or improved by estrogen supplementation. Estrogens are C-18 steroids synthesized from cholesterol in the ovary premenopausally and in the peripheral tissue in postmenopausal women.

Seasonal effect upon excision of acquired melanocytic proliferations.

Background: Acquired melanocytic proliferations (AMPs) are excised throughout the year. Questions exist concerning seasonal variation in these excisions.

Objective: To investigate whether AMPs are removed more often during the spring-summer seasons than in the fall-winter and whether the percentage of benign nevi, dysplastic nevi and melanoma varies according to season.