Physico-chemical and toxico-hygienic aspects of using ethylene oxide for the sterilization of articles for medical use. Part 2. Toxicity and risk of ethylene oxide entering the organism by non-inhalation routes.

Results of investigation of toxicity of ethylene oxide (EO) entering the organism by routes other than inhalation (subcutaneous, intramuscular, intraperitoneal, intravenous) have demonstrated that the substance causes intoxication characterized by polytropic effect on many vitally important organs and systems. The changes in most of the indices under study show a phasic character and dose-time dependence. In both the acute and chronic effect, impairment of the state of the nervous system, the liver, kidney, blood and reactivity of the organism come to the foreground.

Elaboration and testing of insecticidal varnish in aerosol containers for the control of synanthropic cockroaches.

A formula for the filling of aerosol containers has been elaborated on the basis of a mixture of hexachlorocyclohexane (HCH) gamma isomer and tetrametrin, in a ratio 3:1 with the addition of furniture varnish NC-62 to produce the film, Khladon 11/12 (5050) served as propellent. The study of the process of crystallization of the insecticides on the surface of the film has shown that the effectiveness of insecticidal varnishes is the higher, the smaller the size of the crystals and the easier they can be removed from the surface of the film. This can be achieved by including tetrametrin along with HCH gamma isomer in the formula.

Physico-chemical and toxicologo-hygienic aspects of using ethylene oxide for the sterilization of medical appliances. Part I. Sorption and diffusion of ethylene oxide in polymeric materials.

Sorption ability of polymeric materials for medical purposes was studied with respect to the sterilizing gas - ethylene oxide - at 23, 35 and 55 degrees C. Sorption coefficients of ethylene oxide (EO) for the materials under study were calculated on the basis of results. Investigation of the kinetics of desorption of EO from the polymeric materials for medical purposes has shown that its content changes exponentially depending on the time of degassing.

Preparation and study of composite insecticido-repellent aerosols.

Insecticido-repellent mixtures sprayed on clothes, nets etc. are useful as a means of protection against attack by bloodsucking arthropods. These sprays provide repellence of insects sensitive to the repellent and kill those that are only weakly repellent sensitive.