Publications by authors named "Glauco Cappellini"
Unlabelled: The fixed-dose combination of beclometasone dipropionate/formoterol fumarate (BDP/FF) delivered pressurised metered-dose inhaler (pMDI) has demonstrated efficacy in chronic obstructive pulmonary disease (COPD), in studies predominantly conducted in Caucasian adults. The current study evaluated the efficacy and safety of BDP/FF pMDI in Chinese patients with COPD, as part of registration for COPD in China. This double-blind, double-dummy, randomised, parallel-group study was conducted in patients with COPD of Chinese ethnicity aged ≥40 years.
View Article and Find Full Text PDFIntroduction: Inhaled corticosteroid/formoterol fumarate (ICS/FF) as needed is recommended by the Global Initiative for Asthma (GINA) as sole therapy in adults with mild asthma, with low-dose maintenance ICS plus short-acting β-agonist (SABA) as an alternative. SABA alone is no longer recommended. Given these changes in recommendations, the observational PRIME study aimed to describe real-world treatment patterns in mild asthma in Europe.
View Article and Find Full Text PDFArticle Synopsis
- The study compares the effectiveness of two inhalation devices for delivering beclomethasone dipropionate plus formoterol fumarate (BDP/FF) in Chinese adults with asthma: a pressurized metered-dose inhaler (pMDI) and a breath-activated dry powder inhaler (DPI) called NEXThaler.
- After a four-week period where all patients initially used the pMDI, they were randomly assigned to use either the pMDI or DPI for an additional 12 weeks, measuring their pre-dose morning peak expiratory flow (PEF) as the primary outcome.
- Results showed that both devices delivered similar PEF outcomes, with around 88% of patients completing the
Background: In animal models and clinical trials, statins are reported as effective in reducing cholesterol levels and lowering the risk of cardiovascular diseases. We have aggregated the findings in animal models - mice, rats and rabbits - using the technique of systematic review and meta-analysis to highlight differences in the efficacy of statins.
Materials And Methods: We searched Medline and Embase.
Background: Few data on the thromboembolic (TE) risk of paroxysmal and persistent atrial fibrillation (AF) are available. This study aimed to assess the incidence of TE events in paroxysmal and persistent AF.
Methods: We performed a subset post hoc analysis of 771 patients with paroxysmal and 463 with persistent AF enrolled in the multicenter, prospective, randomized, double-blind, placebo-controlled GISSI-AF trial - comparing the efficacy of valsartan versus placebo in preventing AF recurrences - where the choice of antithrombotic treatment was left to the judgment of the referring physician.