Publications by authors named "Glaser C"

Article Synopsis
  • * The study introduces enhanced modeling techniques for neutrino flux and detector response, and it distinguishes between starting (inside) and throughgoing (outside) neutrino interaction events to improve energy resolution.
  • * The findings indicate a best-fit point for the 3+1 model with sin²(2θ_{24})=0.16 and Δm_{41}²=3.5 eV², supporting previous studies while showing consistency with no evidence of sterile neutrinos, as reflected
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In pharmacoepidemiology, robust data are needed to judge the impact of drug treatment on pregnancy, pregnancy outcomes and breast-fed infants. As pregnant and breastfeeding women are usually excluded from randomised clinical trials, observational studies are required. One of those data sources are pregnancy registers specifically developed to focus on certain diseases or disease groups.

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Purpose: Kono-S anastomosis, an antimesenteric, functional, end-to-end handsewn anastomosis, was introduced in 2011. The aim of this meta-analysis is to evaluate the safety and effectivity of the Kono-S technique.

Methods: A comprehensive search of MEDLINE (PubMed), Embase (Elsevier), Scopus (Elsevier), and Cochrane Central (Ovid) from inception to August 24th, 2023, was conducted.

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  • The study assessed a California COVID-19 antigen testing program in K-12 schools, involving self-swabbing and testing by trained school personnel, from August 2021 to May 2022.
  • It included over 944,000 participants, with results showing the Abbott BinaxNOW antigen test had an 81.2% sensitivity and a 99.6% specificity compared to PCR tests.
  • The findings concluded that a school-based testing program is feasible and effective, offering a model for managing future infectious disease outbreaks.
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Introduction: Obturator hernias are rare, occur mainly in slender people and predominantly in females. Underlying pathology of the obturator hernia is a weakening of the obturator membrane. The obturator hernia is situated between the pubic and ischial bones and is therefore clinically occult.

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  • * A new rickettsial pathogen, Rickettsia sp. CA6269, was identified in two patients in northern California, causing severe illness similar to Rocky Mountain spotted fever.
  • * The study highlights potential misidentification of Rickettsia sp. CA6269 as R. rickettsii due to cross-reactivity in diagnostic tests and introduces a specific real-time PCR for accurate detection and understanding of this emerging pathogen.
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  • - The study presents a measurement of astrophysical tau neutrinos using 9.7 years of data from the IceCube observatory, identifying seven candidate events with energies between 20 TeV and 1 PeV.
  • - Convolutional neural networks were used to analyze simulated event images, helping to estimate the parent tau neutrino energy to be around 200 TeV while facing a background of about 0.5 events primarily from non-tau astrophysical neutrinos.
  • - The results confirmed the presence of astrophysical tau neutrinos at a 5σ significance level, aligning with existing IceCube measurements and theoretical predictions regarding neutrino flux and oscillations.
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Objective: Transcatheter arterial embolization (TAE) is a novel minimally invasive therapy for painful tendinopathy in patients with pain refractory to conservative management. The purpose of this study was to evaluate evidence on the efficacy of TAE for tendinopathy related pain.

Materials And Methods: Using Embase, PubMed, and Web of Science, a systematic review and meta-analysis was performed to identify studies evaluating TAE for painful tendinopathy.

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  • Research indicates that cannabinoids may be helpful in treating migraines, but there's limited information about their use among headache patients.
  • A study surveyed 1,373 patients at a headache clinic, revealing that over half had used cannabis-based products for migraines, mainly for headache relief and sleep issues.
  • Participants reported significant improvements in migraine symptoms and related conditions, with many reducing or eliminating conventional medications, while side effects were relatively uncommon.
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Background: Individuals with anti-citrullinated protein antibodies (ACPAs) and subclinical inflammatory changes in joints are at high risk of developing rheumatoid arthritis. Treatment strategies to intercept this pre-stage clinical disease remain to be developed. We aimed to assess whether 6-month treatment with abatacept improves inflammation in preclinical rheumatoid arthritis.

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This history page in the series "Leaders in MSK radiology" is dedicated to the memory and achievements of the German radiologist Gustav Peter Bucky who invented the Bucky diaphragm grids. He wanted to become an engineer but bowed to his parents' wishes and went to medical school. By using his technical skills, he made revolutionary contributions to the early X-ray technique.

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Background: Artificial Intelligence provides numerous applications in the healthcare sector. The main aim of this study is to evaluate the extent of the current application of artificial intelligence in thyroid diagnostics.

Methods: Our protocol was based on the Scoping Reviews extension of the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA-ScR).

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Introduction: The SARS-CoV-2 pandemic represented a formidable scientific and technological challenge to public health due to its rapid spread and evolution. To meet these challenges and to characterize the virus over time, the State of California established the California SARS-CoV-2 Whole Genome Sequencing (WGS) Initiative, or "California COVIDNet". This initiative constituted an unprecedented multi-sector collaborative effort to achieve large-scale genomic surveillance of SARS-CoV-2 across California to monitor the spread of variants within the state, to detect new and emerging variants, and to characterize outbreaks in congregate, workplace, and other settings.

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In this retrospective study, we measured enterovirus D68 (EV-D68) genomic RNA in wastewater solids longitudinally at 2 California, USA, wastewater treatment plants twice per week for 26 months. EV-D68 RNA was undetectable except when concentrations increased from mid-July to mid-December 2022, which coincided with a peak in confirmed EV-D68 cases.

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Article Synopsis
  • Calcific tendinitis is a common muscle condition characterized by painful calcium crystal deposits in tendons, often causing severe shoulder pain and limited movement, with 10-30% of cases being more complex.
  • Standard imaging methods like X-ray and ultrasound are essential for diagnosis, while MRI and CT may be used for further assessment and to identify complications.
  • A thorough evaluation of symptoms alongside imaging results is important for determining treatment plans and prognosis, as well as recognizing potential complications and related health issues.
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The cerebellum communicates with brain areas critically involved in control of goal-directed behaviors including the prefrontal and orbitofrontal cortices and midbrain and basal ganglia structures. In particular, the posterior cerebellum is important for cognitive flexibility and has been implicated in alcohol and drug-related memory. We hypothesized that the cerebellum, through its multiple connections to reward-related brain circuitry, regulates alcohol consumption.

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Encephalitis is a devastating neurologic disease often complicated by prolonged neurologic deficits. Best practices for the management of adult patients include universal testing for a core group of etiologies, including herpes simplex virus (HSV)-1, varicella zoster virus (VZV), enteroviruses, West Nile virus, and anti-N-methyl-D-aspartate receptor (anti-NMDAR) antibody encephalitis. Empiric acyclovir therapy should be started at presentation and in selected cases continued until a second HSV-1 polymerase chain reaction test is negative.

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  • The study aimed to investigate how different levels of expertise among readers affect the agreement and accuracy of diagnosing adhesive capsulitis of the shoulder using various imaging signs.* -
  • Three readers independently evaluated 180 contrast-enhanced MRIs (60 with adhesive capsulitis and 120 without), focusing on both non-enhanced and contrast-enhanced imaging signs.* -
  • Results showed that contrast-enhanced imaging provided significantly higher agreement (ICC 0.79-0.80) and diagnostic performance (AUCs 95.1-96.6%) than non-enhanced signs (ICC 0.37-0.45, AUCs 61.5-85.9%), although the combination of signs did
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The origin of high-energy cosmic rays, atomic nuclei that continuously impact Earth's atmosphere, is unknown. Because of deflection by interstellar magnetic fields, cosmic rays produced within the Milky Way arrive at Earth from random directions. However, cosmic rays interact with matter near their sources and during propagation, which produces high-energy neutrinos.

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Article Synopsis
  • During the COVID-19 pandemic, many public health labs struggled to manage the huge amount of virus data they needed to analyze.
  • The California Department of Public Health teamed up with a company to create a new system called California COVIDNet to help track the SARS-CoV-2 virus using data from over 40 labs.
  • They used cool technology and shared resources to make the system work better, and now California COVIDNet is also helping with other important health threats.
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