Detecting play behaviour in weaned dairy calves using accelerometer data.

This research paper describes a validation study evaluating the ability of IceTag accelerometers (Peacock Technology, UK) to detect play behaviour in weaned dairy calves. Play behaviour is commonly observed in young animals and is regarded as an indicator of positive welfare states. Eight Holstein Friesian calves aged three to five months old were monitored using leg-mounted accelerometers for 48 h.

Mixed practice was my plan…then cattle health specialisation caught my attention.

Gaining experience in mixed practice was the starting point for Nicola Gladden, then locuming and travel gave her the space to decide which career route to follow next, choosing a residency pathway.

Pharmacokinetics of bromoform in dairy heifers.

Aims: To determine the pharmacokinetics in dairy heifers after oral and IV administration of bromoform, a potential antimethanogenic agent found in red seaweed, spp.

Methods: Twenty-four dairy heifers with a mean weight of 319 (SD 36.9) kg were used.

Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller.

The Chaperonin Containing Tailless polypeptide 1 (CCT) complex is an essential protein folding machine with a diverse clientele of substrates, including many proteins with β-propeller domains. Here, we determine the structures of human CCT in complex with its accessory co-chaperone, phosducin-like protein 1 (PhLP1), in the process of folding Gβ, a component of Regulator of G protein Signaling (RGS) complexes. Cryoelectron microscopy (cryo-EM) and image processing reveal an ensemble of distinct snapshots that represent the folding trajectory of Gβ from an unfolded molten globule to a fully folded β-propeller.

Sepsis Program Activities in Acute Care Hospitals - National Healthcare Safety Network, United States, 2022.

Sepsis, life-threatening organ dysfunction secondary to infection, contributes to at least 1.7 million adult hospitalizations and at least 350,000 deaths annually in the United States. Sepsis care is complex, requiring the coordination of multiple hospital departments and disciplines.

Visualizing the chaperone-mediated folding trajectory of the G protein β5 β-propeller.

The cytosolic Chaperonin Containing Tailless polypeptide 1 (CCT) complex is an essential protein folding machine with a diverse clientele of substrates, including many proteins with β-propeller domains. Here, we determined structures of CCT in complex with its accessory co-chaperone, phosducin-like protein 1 (PhLP1), in the process of folding Gβ, a component of Regulator of G protein Signaling (RGS) complexes. Cryo-EM and image processing revealed an ensemble of distinct snapshots that represent the folding trajectory of Gβ from an unfolded molten globule to a fully folded β-propeller.

Administration of ketoprofen affects post-partum lying behaviours of Holstein dairy cows regardless of whether parturition is assisted.

Background: Assistance at parturition in cattle is common. Although analgesia is commonly provided, its value in terms of welfare improvement is not known. Few previous studies include both parturition assistance and analgesic treatment status as well as appropriate control groups in a factorial design.

Use of a Tri-Axial Accelerometer Can Reliably Detect Play Behaviour in Newborn Calves.

Traditionally, the welfare assessment of farm animals has focused on health and production outcomes. Positive welfare is, however, not merely the absence of negative welfare and is an important part of a life worth living. Play behaviour is widely considered to be an indicator of positive emotions because it is a "luxury" behaviour.

Postpartum ketoprofen treatment does not alter stress biomarkers in cows and calves experiencing assisted and unassisted parturition: a randomised controlled trial.

Dystocia is considered painful and stressful for both the dam and the calf, although systematic evidence of this is limited. Few studies have investigated biochemical markers of stress and pain postpartum and whether any adverse effects are ameliorated by administration of analgesia. In this study, cow-calf pairs experiencing both mild to moderate farmer assistance and no assistance at parturition were randomly assigned to either treatment or placebo group in a two-by-two design (animals subject to veterinary intervention were excluded).

A case report of Mycoplasma wenyonii associated immune-mediated haemolytic anaemia in a dairy cow.

Background And Case Presentation: A three year old, second lactation Holstein dairy cow presented to the Scottish Centre for Production Animal Health and Food Safety, Glasgow University Veterinary School in November 2014 with a history of post-calving vulval/vaginal bleeding nine days prior to presentation, followed by a sudden reduction in milk yield. Subsequent investigations resulted in a diagnosis of immune-mediated haemolytic anaemia secondary to infection with Mycoplasma wenyonii.

Conclusion: This report of a novel presentation of Mycoplasma wenyonii in a dairy cow illustrates the need to consider M.

Survey of internal parasitism and anthelmintic use in farmed deer.

Faecal samples and questionnaires from 115 and 130 farms respectively were used to survey the internal parasite status of the national deer herd and examine current drenching practices. The survey included farms with red deer and wapiti-red deer crosses (Cervus elaphus), and fallow deer (Dama dama). Gastrointestinal nematode eggs were recorded from 84% of all farms, Dictyocaulus viviparus larvae from 85% of all farms, and Elaphostrongylus cervi larvae from 35% of the farms with C.

Experimental tuberculosis in red deer (Cervus elaphus).

This study was designed to investigate experimental Mycobacterium bovis infection of red deer (Cervus elaphus). Three intravenously inoculated deer (dose 10 microg-1000 microg) developed miliary tuberculosis of the lungs and all died within 28 days of being infected. No clinical illnesses were observed in four subcutaneously (dose 1 microg-1000 microg) and three intratracheally (dose 10 microg-100 microg) inoculated deer.