Publications by authors named "Gizem Yaz Aydin"
Article Synopsis
- Ischemia-reperfusion (I/R) injury can cause severe testicular damage and infertility, prompting research on fasudil as a potential protective treatment.
- The study involved 30 male Long-Evans rats divided into groups to compare the effects of fasudil treatment before and after I/R injury against control and untreated injured groups.
- Results showed that fasudil significantly reduces indicators of tissue damage and inflammation, especially when given before detorsion, suggesting it offers protection against I/R injury in testicular tissue.
Coronavirus disease 2019 (COVID-19) has resulted in long-term psychiatric symptoms because of the immunologic response to the virus itself as well as fundamental life changes related to the pandemic. This immune response leads to altered tryptophan (TRP)-kynurenine (KYN) pathway (TKP) metabolism, which plays an essential role in the pathophysiology of mental illnesses. We aimed to define TKP changes as a potential underlying mechanism of psychiatric disorders in post-COVID-19 patients.
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