Publications by authors named "Gizem Tugce Alp"
Objectives: Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis, vascular damage, and immune dysregulation, often leading to muscle abnormalities. This study aimed to evaluate the prevalence of myopenia and myosteatosis in SSc patients using computed tomography (CT) and their associations with clinical features, including lung disease and esophageal dilatation.
Materials And Methods: SSc patients followed at Gazi University Rheumatology Clinic (2000-2024) who had thoracic CT imaging were included.
Article Synopsis
- This study examined the prevalence of sarcopenia (loss of muscle mass and strength) in Turkish women with systemic lupus erythematosus (SLE) and its relationship to disease activity.
- Out of 82 SLE patients, over half exhibited probable sarcopenia, while about 13% were diagnosed with sarcopenia, indicated by significantly lower hand grip strength compared to healthy controls.
- The research concluded that while sarcopenia is common in this population, there was no direct link between sarcopenia and the severity of SLE, suggesting the need for regular assessments of muscle strength in clinical practice.
Objectives: To evaluate the use of calcineurin inhibitors (CNIs), specifically tacrolimus, in unplanned pregnancies with active lupus disease among patients with systemic lupus erythematosus (SLE).
Materials And Methods: The study includes data from pregnancies in women diagnosed with SLE at Gazi University Hospital in Ankara, Türkiye, between January 2010 and July 2022. The study categorized pregnancies into planned and unplanned groups based on lupus nephritis presence, emphasizing the need for inactive lupus disease for at least 6 months before attempting conception in planned pregnancies.