Systemic Anti-Inflammatory Effects of Isotretinoin: Evaluation of Red Cell Distribution Width to Lymphocyte and Platelet Ratios as New Hematological Markers and Clinical Outcomes in Acne Vulgaris.

Background: Acne vulgaris is a chronic inflammatory skin disease influenced by systemic immune responses. While isotretinoin is the most effective treatment for severe acne, its effects on hematological markers of inflammation, in particular red cell distribution width (RDW)-to-lymphocyte and RDW-to-platelet ratios, remain unclear.

Methods: This retrospective study analyzed 450 acne patients treated with isotretinoin for at least 24 weeks.

Experiences of barbed polydioxanone (PDO) cog thread for facial rejuvenation and our technique to prevent thread migration.

Background: One of the most common nonsurgical options for facial rejuvenation is lifting using threads. Application of polydioxanone (PDO) threads is generally secure and effective procedure, but complications on the involved regions can occur.

Objective: In this study, we shared our experiences of efficacy and safety of PDO thread lifting for facial rejuvenation and presented our technique to prevent the migration of threads.