Publications by authors named "Gizem Erdogan"
Article Synopsis
- - The study evaluated the effectiveness of multiplex real-time polymerase chain reaction (RtPCR) in diagnosing sepsis from whole blood and blood cultures in ICU patients, comparing it to traditional methods over a period from November 2019 to August 2020.
- - Out of 90 patients in the study, 73 had already received antibiotics, and the conventional blood culture was set as the gold standard, revealing varied effectiveness of RtPCR based on the sample type: sensitivity ranged from 11.67% to 89.58% for whole blood and blood culture respectively.
- - The results showed that while RtPCR from blood culture bottles had higher sensitivity and quicker reporting times than traditional methods, it also exhibited a lower specificity compared to Rt
Background: Signal recognition particle (SRP) promotes co-translational translocation of the proteins through or into the endoplasmic reticulum membrane and it also has elongation arrest function. SRP9 is one of the six protein subunits of SRP and functions in elongation arrest activity by forming a heterodimeric structure with SRP14. It is one of the substrates of ADAR, which has been found to have a role in breast cancer.
View Article and Find Full Text PDFEarly reporting of the antibiotic susceptibility testing (AST) results is essential for the survival of sepsis patients. In 2019, European Committee on Antimicrobial Susceptibility Testing (EUCAST) published a proposal to detect antimicrobial susceptibility from positive blood culture bottles with a rapid antimicrobial susceptibility test (RAST) method in a maximum of eight hours. In this study, it was aimed to evaluate the EUCAST RAST method in blood culture bottles that resulted with positive signal in BacT/ALERT (bioMérieux, France) blood culture system and that showed gram-negative bacteria with single morphology with Gram stain.
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