Changes in hematopoietic stem cell numbers following acute exercise in non-athlete marathon runners.

Purpose: Hematopoietic stem cell (HSC) transplant is one of the curative methods for some patients with hematological malignancies. Granulocyte colony-stimulating factor (G-CSF) is the most common drug used to mobilize CD34 cells, generally found in small numbers. Recent evidence showed that exercise causes transient mobilization in HSC.