Evaluation of Factors Affecting the Health-Related Quality of Life in End-Stage Renal Disease Patients Receiving Hemodialysis Treatment in Northern Cyprus.

Introduction Health-related quality of life (HR-QoL) is recognized as an important predictor of mortality and morbidity in end-stage renal disease (ESRD) patients receiving hemodialysis (HD). The goal of this study was to obtain HR-QoL scores using the Kidney Disease and Quality of Life questionnaire (KDQOL-36) (RAND Corporation, Santa Monica, CA) and to assess the factors affecting HR-QoL in ESRD patients receiving HD. Methods A multicenter cross-sectional study was performed using the KDQOL-36 for the assessment of HR-QoL of ESRD patients receiving HD in Northern Cypriot state hospitals.

Exploring University Students' Perspectives on Animal Experimentation: Insights From a Cross-Sectional Study.

Introduction Attitudes toward animal experimentation are rapidly evolving with time. This cross-sectional study intends to assess the attitudes of university students at Eastern Mediterranean University toward animal research based on different factors and lifestyle choices. Materials and methods Stratified random sampling was used.

The development of a self-evaluation scale for simulation laboratory practices.

Background: Simulation is an important learning-teaching tool for integrating theory and practice in nursing education.

Objective: The aim of this study was to develop and to conduct the validity and reliability of a self-evaluation scale for simulation laboratory practices (SES-SLP) with undergraduate nurses.

Methods: The study sample consisted of 220 undergraduate nursing students.

Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.

In continuation of our efforts to develop new derivatives as hepatitis C virus (HCV) NS5B inhibitors, we synthesized novel 5-arylidene-4-thiazolidinones. The novel compounds 29-42, together with their synthetic precursors 22-28, were tested for HCV NS5B inhibitory activity; 12 of these compounds displayed IC50 values between 25.3 and 54.