Publications by authors named "Gizela Bambo"
Objective: The effectiveness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is threatened by increasing SP-resistance in Africa. We assessed the level of SP-resistance markers, and the clinical and parasitological effectiveness of IPTp-SP in southern Mozambique.
Methods: P.
Background: Information on the frequency and clinical features of advanced HIV disease (AHD) in pregnancy and its effects on maternal and perinatal outcomes is limited. The objective of this study was to describe the prevalence and clinical presentation of AHD in pregnancy, and to assess the impact of AHD in maternal and perinatal outcomes in Mozambican pregnant women.
Methods: This is a prospective and retrospective cohort study including HIV-infected pregnant women who attended the antenatal care (ANC) clinic at the Manhiça District Hospital between 2015 and 2020.
Article Synopsis
- The study assessed the impact of the Rotarix® rotavirus vaccine in Mozambique, focusing on its effect on hospitalizations due to childhood gastroenteritis after its introduction in September 2015.
- Findings showed a significant decrease in the prevalence of acute gastroenteritis from 19% pre-vaccine to 10% post-vaccine, preventing 40% of expected cases overall and 84% of lab-confirmed rotavirus cases in infants.
- The incidence of rotavirus was also drastically lower post-vaccination, with an 11.8-fold decrease, most notably in infants, highlighting the vaccine's important role in protecting vulnerable populations from severe diarrhea and related hospitalizations.
Objectives: This retrospective analysis performed in Manhiça, Southern Mozambique, aimed to describe the frequency of post-malarial anemia (measured as a decrease of hematocrit ≥10%) and the need for blood transfusions in children with severe malaria treated with intravenous quinine or parenteral artesunate.
Methods: All children <15 years admitted with a parasitologically-confirmed diagnosis of malaria from 1 January 2003 to 31 December 2017, alive at hospital discharge, and with at least one measurement of hematocrit within 28 days after hospital discharge, detected by passive case detection, were included.
Results: The overall prevalence of post-malarial anemia observed in the study was 23.