Publications by authors named "Giusy Schipani"

Article Synopsis
  • - This study investigated the link between environmental heavy metals and the risk of actinic keratosis (AK) and non-melanoma skin cancer (NMSC) by analyzing hair samples from patients and healthy controls.
  • - A total of 31 patients with AK/NMSC and 34 healthy participants were assessed for exposure to metals like arsenic and chromium, using statistical tests to determine significance.
  • - Results showed higher levels of arsenic and chromium in patients with AK/NMSC compared to controls, suggesting these metals may play a significant role in increasing skin cancer risk.
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Mycosis fungoides (MF) is a cutaneous malignant lymphoma with an extended clinical course. MF presents in series of dermatological manifestations, beginning with patches and plaques of the skin, and eventually evolving into tumours. Often MF can occur for extended periods without worsening of external symptoms, while the disease advances internally in organs such as lymph nodes, liver, spleen, lung, bone marrow, gastrointestinal tract, pancreas and kidney.

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Background: Acne vulgaris is a chronic inflammatory disease that frequently occurs in adolescence. This common condition is often treated with topical or systemic therapies according to severity. Photodynamic therapy (PDT) with topical delta-aminolaevulinic acid is a novel drug-sparing, but time-consuming approach.

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Article Synopsis
  • Topical oxygen therapy is gaining popularity in dermatology as a cosmetic procedure, yet there is limited literature on its effectiveness as a treatment option for various skin conditions.
  • Four studies were conducted using topical oxygen therapy for conditions like hair loss, mild and moderate acne, and chronic skin diseases such as psoriasis and atopic dermatitis.
  • The results showed that topical oxygen therapy improved outcomes in hair loss and mild acne treatments, but further research with control groups is needed to better assess its overall effectiveness.
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Introduction: The evaluation of Acne using ordinal scales reflects the clinical perception of severity but has shown low reproducibility both intra- and inter-rater. In this study, we investigated if Artificial Intelligence trained on images of Acne patients could perform acne grading with high accuracy and reliabilities superior to those of expert physicians.

Methods: 479 patients with acne grading ranging from clear to severe and sampled from three ethnic groups participated in this study.

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Basal cell carcinoma (BCC), the most common type of skin cancer in the world, usually arises in sun-exposed areas of the skin. The therapeutic approach to periocular BCC has changed in the last few years. Currently the treatment, considering the delicate localization of the disease, must not only ensure complete recovery from the neoplastic disease, but must also satisfy functional and aesthetic criteria.

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Background: Head and neck melanoma is a clinical challenge. Indeed, cutaneous head and neck melanoma shows a worse prognosis in comparison to melanomas of other body sites. Although the emphasis on facial cosmetic preservation plays a pivotal role in comparison to other body areas, specific Facial Aesthetic Units (FAU) could also play a key role in the prognostic evaluation of the malignancy.

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