Publications by authors named "Giuseppina M Farella"

Article Synopsis
  • A study was conducted to create and validate a new protocol called THD-US for detecting tendinopathy in patients with hemophilia using ultrasound.
  • Twenty male patients with hemophilic arthropathy were evaluated, resulting in analyses of 200 tendons for abnormalities such as structural changes, hyperemia, and calcifications.
  • The THD-US protocol offers a standardized and efficient way to assess tendon issues in hemophilia patients, which could lead to better management and outcomes for these individuals.
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Background: In 2020, a multiprofessional panel was set up in collaboration with the Italian FightTheStroke Foundation family association to produce evidence-based recommendations for the management and neuromotor rehabilitation of persons with cerebral palsy aged 2-18 years to implement in clinical practice in Italy.

Methods: The recommendations of these care pathways were developed according to the American Academy for Cerebral Palsy and Developmental Medicine guidelines for Care Pathways Development and the Grading of Recommendations Assessment Development and Evaluation working group for adoption, adaptation, or de novo development of recommendations from high-quality guidelines (GRADE-ADOLOPMENT).

Results: Four strong positive recommendations were developed regarding comprehensive management, and twenty-four addressed neuromotor treatment.

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Article Synopsis
  • Hemophilia is an inherited bleeding disorder leading to joint bleeding (hemarthrosis), and this study aims to evaluate the condition of tendons in affected joints of patients with hemophilic arthropathy and suggest eccentric exercise rehabilitation.
  • The study used ultrasound alongside various clinical scales to assess the tendons in 20 patients, finding that while most tendons appeared normal, some showed significant alterations and damage in those with severe joint issues.
  • The findings indicate that tendons in patients with hemophilic arthropathy are negatively impacted by joint disease, but rehabilitation with eccentric exercises is a safe and effective treatment option to enhance tendon properties.
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Background: Evidence regarding the management of several aspects of cerebral palsy improved in recent years. Still, discrepancies are reported in clinical practice. Italian professionals and stakeholders expressed the need of setting up updated, evidenced-based, shared statements, to address clinical practice in cerebral palsy rehabilitation.

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Progressive pseudorheumatoid dysplasia (PPRD) is an autosomal recessive inherited skeletal dysplasia characterized by progressive non-inflammatory arthropathy affecting primarily the articular cartilage. Currently, little is known about the functional musculoskeletal aspects of these patients. In particular, an abnormal gait pattern has been described, without a clear hypothesis of the underlying causes in terms of muscular activity.

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