Towards an Innovative Sensor in Smart Capsule for Aerial Drones for Blood and Blood Component Delivery.

Aerial drone technology is currently being investigated worldwide for the delivery of blood components. Although it has been demonstrated to be safe, the delivered medical substances still need to be analyzed at the end of the flight mission to assess the level of haemolysis and pH prior to the use in a patient. This process can last up to 30 min and prevent the time saved using drone delivery.

A Novel Pressure-Controlled Revolute Joint with Variable Stiffness.

The compliance and deformability of soft robotics allow human-machine interactions in a safe manner without the need of sophisticated control systems inherent in rigid-body robotic devices. However, these advantages introduce controllability and predictability challenges. In this study, we propose a novel fluidic-driven variable stiffness revolute joint (VSRJ) based on hybrid soft-rigid approach to achieve adjustable compliance while addressing the abovementioned challenges.

The Photoinactivation of by a Novel LED-Based Device.

The rise of antibiotic resistance is the main cause for the failure of conventional antibiotic therapy of infection, which is often associated with severe gastric diseases, including gastric cancer. In the last years, alternative non-pharmacological approaches have been considered in the treatment of infection. Among these, antimicrobial PhotoDynamic Therapy (aPDT), a light-based treatment able to photoinactivate a wide range of bacteria, viruses, fungal and protozoan parasites, could represent a promising therapeutic strategy.

Hybrid Soft-Rigid Actuators for Minimally Invasive Surgery.

Fluidic mechanisms have stimulated research and development in minimally invasive surgery instrumentations, because of their good performance in limited size and their force/torque generation with respect to other types of actuation systems. Fluidic solutions can be divided in two major classes: (i) elastic fluidic actuators and (ii) piston-cylinder actuators. Elastic fluidic actuators generate lower forces with smaller displacements; nevertheless, piston-cylinder solutions require seals, which can generate friction and require maintenance costs for a good reliability.

An Innovative Wireless Endoscopic Capsule With Spherical Shape.

This paper aims to contribute to the advancement of the Wireless Capsule Endoscopy (WCE) field for ColoRectal Cancer (CRC) screening, by developing all electronic circuits to build an innovative wireless endoscopic capsule with a spherical shape, conceived to reduce the friction during its locomotion and thus improving patient's acceptability. The proposed capsule embeds an image sensor with optics and Light Emitting Diodes (LEDs), a control unit with a telemetry module, an actuation system, a battery with a smart recharging circuit able to recharge in 20 minutes, a smart power-on circuit and a localization module. Everything is devised to fit in a small spherical shape with a diameter of 26 mm and a weight of 12.

A miniaturized robotic platform for natural orifice transluminal endoscopic surgery: in vivo validation.

Background: Natural orifice transluminal endoscopic surgery (NOTES) involves accessing the abdominal cavity via one of the body natural orifices for enabling minimally invasive surgical procedures. However, the constraints imposed by the access modality and the limited available technology make NOTES very challenging for surgeons. Tools redesign and introduction of novel surgical instruments are imperative in order to make NOTES operative in a real surgical scenario, reproducible and reliable.

An innovative adaptive control strategy for sensorized left ventricular assist devices.

Nowadays advanced heart failure is mainly treated through heart transplantation. However, the low availability of donors makes the research of alternative therapies urgent. Continuous-flow left ventricular assist devices (LVADs) are going to assume a more significant role in assisting the failing heart.

An integrated system for wireless capsule endoscopy in a liquid-distended stomach.

The design and development of a functional integrated system for gastroscopy is reported in this paper. The device takes advantage of four propellers enabling locomotion in a liquid environment and generating a maximum propulsive force of 25.5 mN.

Investigation of bioinspired gecko fibers to improve adhesion of HeartLander surgical robot.

HeartLander is a medical robot proposed for minimally invasive epicardial intervention on the beating heart. To date, all prototypes have used suction to gain traction on the epicardium. Gecko-foot-inspired micro-fibers have been proposed for repeatable adhesion to surfaces.

Propeller-based wireless device for active capsular endoscopy in the gastric district.

An innovative approach to active locomotion for capsular endoscopy in the gastric district is reported in this paper. Taking advantage of the ingestion of 500 ml of transparent liquid by the patient, an effective distension of the stomach is safely achieved for a timeframe of approximately 30 minutes. Given such a scenario, an active swallowable capsule able to navigate inside the stomach thanks to a four propeller system has been developed.