Publications by authors named "Giuseppe Salvatore Murgida"
Clinical Features, Management, and Recurrence of Acute Ischemic Stroke Occurring in Patients on Oral Anticoagulant Treatment for Nonvalvular Atrial Fibrillation: A Real-World Retrospective Study.
Elisa Grifoni Beatrice Pagni Teresa Sansone Mariella Baldini Elisabetta Bertini Giuseppe Salvatore Murgida
Neurologist
November 2024
Article Synopsis
- The study investigated how acute ischemic stroke (AIS) affects patients with nonvalvular atrial fibrillation (NVAF) who are using oral anticoagulants (OA), specifically comparing direct oral anticoagulants (DOAC) and vitamin K antagonists (VKA).
- A total of 169 patients were examined, revealing that those on VKA had higher in-hospital mortality rates and poor outcomes 90 days after the stroke compared to DOAC users.
- The researchers found that switching anticoagulants did not impact stroke recurrence rates, suggesting that further extensive research is needed to optimize treatment for AIS in OA patients.
Article Synopsis
- The study investigates predictive factors for hemorrhagic transformation (HT) in acute ischemic stroke patients using retrospective data analysis.
- A new predictive score, the Hemorrhagic Transformation Empoli score (HTE), incorporates factors such as NIHSS score, cardioembolic causes, and previous stroke history to assess HT risk.
- The HTE score outperforms five existing prediction scores, showing good predictive power with an AUC of 0.785, indicating its potential for clinical use.
Few data are available on age-related burden and characteristics of embolic stroke of undetermined source (ESUS) in the real world clinical practice. The aim of our study was to provide information about it. We retrospectively analyzed data of patients consecutively admitted to our Stroke Unit along 1 year (2017, November 1st-2018, October 31st).
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