Publications by authors named "Giuseppe Nucera"

Article Synopsis
  • Scientists have found new types of T-cell disorders that can happen in the stomach and skin, which show specific changes in their T-cell receptors and have a certain unactive type of T-cells.
  • In this study, a case of a 39-year-old woman showed unusual growth of T-cells in her uterus, matching the features of these new disorders.
  • The researchers think this might come from a special group of T-cells in the uterus that grew larger due to many encounters with a specific type of cell found during pregnancy.
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Background: A progressive delay in the age of first conception results in an increased frequency of endometrial cancer patients in reproductive age and desiring childbearing.

Case: A 38-year-old infertile woman with stage I endometrioid adenocarcinoma was treated with gonadotropin releasing hormone agonist (GnRHa) and levonorgestrel-releasing intrauterine device (LNG-IUD). After disease remission, she underwent a controlled ovarian stimulation for standard in vitro fertilization (IVF) program and had a pregnancy delivering a healthy male baby.

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The new Italian law on assisted reproduction technology rules that no more than three oocytes can be fertilized at one time, and that all embryos obtained must be transferred to the maternal uterus simultaneously. The aim of the present study was to investigate the influence of the new law on spontaneous embryonic/fetal losses through comparison of data collected over an identical period of time: the first year of application of the new law compared with the same time period 1 year before (March 10, 2004 to March 9, 2005 versus March 10, 2003 to March 9, 2004). A total of 271 clinical pregnancies were analysed.

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Survivors of the "vanishing" twin syndrome, which occurred in dichorionic twins only, and singletons that began as singletons, had similar mean gestational duration and birth weights, as well as similar frequencies of maternal and neonatal complications. This similarity persisted when conventional IVF and IVF plus ICSI cases were separately evaluated.

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Objective: To determine whether embryo quality is associated with early spontaneous loss rates in twin and singleton pregnancies after IVF/intracytoplasmic sperm injection (ICSI).

Design: Retrospective, single center analysis.

Setting: The Center of Reproductive Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.

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Objective: To determine whether pregnancies after IVF, with and without intracytoplasmic sperm injection (ICSI), have different early spontaneous loss rates.

Design: Retrospective analysis of IVF/ICSI dataset.

Setting: The Center of Reproductive Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.

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Objectives: The purpose of this study was to determine the early spontaneous loss rate in multiple pregnancies following assisted reproductive technology (ART).

Study Design: Analysis of pregnancies following ART as related to the initial number of embryos and maternal age was performed.

Results: At least one spontaneous loss was observed in 47.

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