Publications by authors named "Giuseppe Nano"

Polluted air streams can be purified using biological treatments such as biotrickling filtration, which is one of the most widely accepted techniques successfully tuned to treat a wide variety of exhausted gaseous streams coming from a series of industrial sectors such as food processing, flavor manufacturers, rendering, and composting. Since the degradation of a pollutant occurs at standard pressure and temperature, biotrickling filtration, whether compared with other more energy-demanding chemical-physical processes of abatement (such as scrubbing, catalytic oxidation, regenerative adsorption, incineration, advanced oxidation processes, etc.), represents a very high energy-efficient technology.

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Dust pollution is a complex problem of growing interest because of its environmental, health, economic and political impact. Environmental impact assessment methods for dust pollution management are often based on the simulation of dust dispersion, which requires a precise characterization of the source term and of the source parameters. The source term model should be as simple and as accurate as possible and requires low time consumption in order to be easily connected to a more complex algorithm for the dispersion calculations.

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Indoor air quality influences people's lives, potentially affecting their health and comfort. Nowadays, ventilation is the only technique commonly used for regulating indoor air quality. CO₂ is the reference species considered in order to calculate the air exchange rates of indoor environments.

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Efficient targeting in tumor therapies is still an open issue: systemic biodistribution and poor specific accumulation of drugs weaken efficacy of treatments. Engineered nanoparticles are expected to bring benefits by allowing specific delivery of drug to the tumor or acting themselves as localized therapeutic agents. In this study we have targeted epithelial ovarian cancer with inorganic nanoparticles conjugated to a human antibody fragment against the folate receptor over-expressed on cancer cells.

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Candle composition is expected to influence the air pollutants emissions, possibly leading to important differences in the emissions of volatile organic compounds and polycyclic aromatic hydrocarbons. In this regard, the purity of the raw materials and additives used can play a key role. Consequently, in this work emission factors for some polycyclic aromatic hydrocarbons, aromatic species, short-chain aldehydes and particulate matter have been determined for container candles constituted by different paraffin waxes burning in a test chamber.

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Targeted radioimmunotherapy has been recently clinically validated and approved for the treatment of cancer by the US Food and Drug Administration. This therapeutic approach employs monoclonal antibodies directed to cancer-related, cell-surface antigens coupled to beta-emitting nuclides. 90Y is one of the most useful radioisotopes in the development of antibody based radioimmunotherapy and evaluation of the pharmacokinetic profile for 90Y-radiopharmaceuticals is usually performed by radiochemical methods.

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The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2 (CXCR2). (R)-Ketoprofen (1) was previously reported to be a potent and specific noncompetitive inhibitor of CXCL8-induced human PMNs chemotaxis.

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