Publications by authors named "Giuseppe La Greca"
Background: A large percentage of peritoneal dialysis (PD) patients being treated with standard lactate-containing solutions tend to have serum bicarbonate concentrations below or above the normal range. The inter-patient variability of serum bicarbonate is a result of many influences and it may be appropriate to adjust the bicarbonate concentration in the peritoneal dialysis fluid (PDF) to the current serum bicarbonate in the individual patient.
Methods: Two concentrations of bicarbonate in PDF were compared in this study (34 and 39 mmol/l).
Article Synopsis
- The study aimed to evaluate whether a specific treatment combining plasma filtration and adsorption could enhance blood circulation and immune response in patients with severe septic shock.
- Conducted as a pilot crossover trial with ten patients, the research compared two treatment methods over 10 hours and measured changes in blood pressure, norepinephrine use, and immune response related to TNF-alpha production.
- Results showed that the combined treatment significantly improved mean arterial pressure and reduced norepinephrine requirements, indicating better hemodynamics, while also enhancing the immune system's responsiveness in most patients.
Very few innovations have characterized the different components of the hemodialyzers in the past 20 years. Most improvements have concerned membrane biocompatibility. In this article, we focus our attention on the most recent advances in hemodialyzer components from the macro design of the unit to the nanostructure of the membrane.
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