Improved selection of canonical proteins for reference proteomes.

The 'canonical' protein sets distributed by UniProt are widely used for similarity searching, and functional and structural annotation. For many investigators, canonical sequences are the only version of a protein examined. However, higher eukaryotes often encode multiple isoforms of a protein from a single gene.

MBDBMetrics: an online metrics tool to measure the impact of biological data resources.

Motivation: There now exist thousands of molecular biology databases covering every aspect of biological data. This database infrastructure takes significant effort and funding to develop and maintain. The creators of these databases need to make strong justifications to funders to prove their impact or importance.