Publications by authors named "Giuseppe Critelli"
Background: Chest pain is frequently reported in Fabry disease (FD). However, its mechanism and clinical relevance are unclear.
Methods And Results: Basal troponin I level, exercise stress test, single-photon emission computed tomography imaging with (99m)Tc sestamibi, coronary angiography with thrombolysis in myocardial infarction (TIMI) frame count and left ventricular angiography and endomyocardial biopsy were obtained in 13 patients with FD with angina.
Coronary artery bypass grafting was performed in a 54-year-old man affected by untreated Fabry's disease. Left internal mammary artery (LIMA) and saphenous vein grafts were implanted. Surgical samples of LIMA revealed diffuse glycosphyngolipid infiltration of smooth muscle cells, whereas SV was normal.
View Article and Find Full Text PDFAims: (1) To correlate atrial tachyarrhythmia (AT) burden of pacemaker-recipient Brady-Tachy syndrome (BTS) patients with a number of diagnostics-derived parameters after 1 month of DDD pacing; (2) to asses whether the activation of atrial overdrive or conventional rate-responsive pacing may affect relevant variables and their correlation.
Methods And Results: After 1 month of DDD pacing, rate-responsive function or persistent atrial overdrive was randomly activated for 3 months, in 92 BTS patients. Some pacemaker diagnostics parameters collected at 1- and 4-month follow-ups were included in multiple linear regression models, whose dependent variable was the Log transformation of AT burden and compared.
Objective: We investigated myocardial perfusion in acute patients with slow coronary flow (SCF) at angiography. Whether impaired myocardial perfusion occurs in acute patients with SCF is unknown.
Methods: We enrolled 28 consecutive patients with SCF in the epicardial coronary arteries with no evidence of significant stenosis.
Aims: The aims of the study were to evaluate the 24-h beat-to-beat heart rate (RR) and blood pressure changes during closed loop stimulation (DDD-CLS) pacing and conventional fixed rate DDD pacing with respect to spontaneous activity.
Methods: We simultaneously and continuously measured beat-to-beat heart rate and blood pressure for 24 h in patients implanted with Inos2+ (Biotronik GmbH, Berlin, Germany). A randomised cross-over comparison of DDD-CLS and DDD pacing was performed by short- and long-term analyses.
Enoximone very low-dose dobutamine stress echocardiography: a new test for detecting viability in severe myocardial dysfunction after acute myocardial infarction.
J Am Soc Echocardiogr
September 2003
Article Synopsis
- A study with 25 patients who experienced their first acute Q-wave anterior myocardial infarction looked at the effects of combining enoximone and dobutamine to evaluate heart muscle viability.
- Using low-dose dobutamine echocardiography and enoximone very low-dose echocardiography, researchers recorded significant improvements in wall-motion scores of severely affected heart areas during drug peak effects and continued monitoring after 4 months post-surgery.
- A strong correlation was found between initial drug effects and long-term heart function in patients, suggesting that enoximone very low-dose echocardiography is a valuable tool for assessing heart muscle viability, especially in difficult cases.
The use of radiofrequency as a means of synchronization and stimulation does not necessitate an external lead, and thus has allowed the construction of an implantable device for long-term treatment of reentry tachycardias. The device is used along with Amiodarone therapy and can be triggered by the patient himself.
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