Control of rotor function in light-driven molecular motors.

A study is presented on the control of rotary motion of an appending rotor unit in a light-driven molecular motor. Two new light driven molecular motors were synthesized that contain aryl groups connected to the stereogenic centers. The aryl groups behave as bidirectional free rotors in three of the four isomers of the 360° rotation cycle, but rotation of the rotors is hindered in the fourth isomer.

Light-induced disassembly of self-assembled vesicle-capped nanotubes observed in real time.

Molecular self-assembly is the basis for the formation of numerous artificial nanostructures. The self-organization of peptides, amphiphilic molecules composed of fused benzene rings and other functional molecules into nanotubes is of particular interest. However, the design of dynamic, complex self-organized systems that are responsive to external stimuli remains a significant challenge.

[Prevention of diabetes mellitus complications and improvement of early diagnosis at a population level, through the implementation of integrated disease management in the Modena region].

We evaluated the effectiveness of diabetes mellitus disease management, implemented in Modena province since ten years, on the prevention of complications and early diagnoses at a population level. Time trends show that diabetic patients had significantly decreasing values over time of age, diabetes duration, and glycated haemoglobin; and increasing percentage over time of new-onset diabetes and optimal glycaemic control. That indicates an improved ability of early diagnosis and care of diabetes mellitus.

Photoresponsive dithienylethene-urea-based organogels with "reversed" behavior.

Dithienylperhydrocyclopentene-bisurea-based low molecular weight gelators are described that function as photoresponsive organogels that show a remarkable gel-to-liquid transition upon irradiation. The two series of derivatives, with and without alkyl spacers between the urea hydrogen bonding groups and the photochromic unit, show different gelation behavior. Upon UV irradiation of the gels, a gel liquified at only 1.

[A retrospective study to evaluate the incidence of medication errors occurring in the prescription and transcription steps of the medication use process].

Medication errors occur frequently in many clinical settings. Various studies have highlighted that, together with adverse drug events, they represent one of the major causes of adverse events occurring in hospitals. The aim of this study was to perform a detailed retrospective medical record review in order to investigate the incidence of medication errors occurring in the prescription and transcription phases of the medication use process.