CO Laser-Assisted Nail Sampling for Mycological Testing in Onychomycosis.

Introduction: Onychomycosis is the most common nail infection, predominantly caused by spp., and is divided into four main types. Confirmatory testing is crucial, but obtaining an adequate sample may be challenging.

Generating depth images of preterm infants in given poses using GANs.

Background And Objectives: The use of deep learning for preterm infant's movement monitoring has the potential to support clinicians in early recognizing motor and behavioural disorders. The development of deep learning algorithms is, however, hampered by the lack of publicly available annotated datasets.

Methods: To mitigate the issue, this paper presents a Generative Adversarial Network-based framework to generate images of preterm infants in a given pose.

Improving Preterm Infants' Joint Detection in Depth Images Via Dense Convolutional Neural Networks.

Preterm infants' spontaneous motility is a valuable diagnostic and prognostic index of motor and cognitive impairments. Despite being recognized as crucial, preterm infant's movement assessment is mostly based on clinicians' visual inspection. The aim of this work is to present a 2D dense convolutional neural network (denseCNN) to detect preterm infant's joints in depth images acquired in neonatal intensive care units.

Acquired Localized (Monodactylous) Longitudinal Pachyonychia and Onychocytic Carcinoma In Situ (2 Cases): Part II.

The authors have recently proposed to use the name pachyonychia as an umbrella term that includes 2 distinctly different entities in the form of congenital pachyonychia and acquired longitudinal pachyonychia. Congenital pachyonychia is defined by a diffuse hyperkeratosis of the nail bed. Acquired longitudinal pachyonychia correspond to the true definition of pachyonychia, that is, a thickened nail plate without subungual keratosis.

Acquired Localized Longitudinal Pachyonychia and Onychomatrical Tumors: A Comparative Study to Onychomatricomas (5 Cases) and Onychocytic Matricomas (4 Cases).

Background: Besides onychomatricoma (OM), which shows a clinical band pattern of nail plate thickening, 2 new onychomatrical tumors with this clinical feature have recently been described: onychocytic matricoma (OCM) and in situ onychocytic carcinoma.

Objective: The purpose of this study was to present 4 cases of OCMs and compare their clinical and histopathologic characteristics with usual OMs.

Methods: We studied 4 cases of OCMs with nail clipping in 3 cases and an extensive immunohistochemical study for hair-related keratins and epithelial keratins.

Onychocytic matricoma presenting as pachymelanonychia longitudinal. A new entity (report of five cases).

Among the tumors of the epidermal appendages, only rare tumors have been proved as differentiating in the direction of the nail. Beside onychomatricoma, we report a new matrical tumor of the nail: onychocytic matricoma (acanthoma of the nail matrix producing onychocytes). The main differential diagnosis of onychocytic matricoma is seborrheic keratosis.

Onychomatricoma in the light of the microanatomy of the normal nail unit.

Onychomatricoma (OM) is an uncommon benign tumor of the nail thought to exhibit differentiation limited toward the nail matrix. Four recent articles from our laboratory have shown, in some respect, a morphological and immunohistochemical homology between the nail unit and the hair follicle at the level of the matrix and isthmus. The purposes of this article are as follows: to investigate whether the sequential pattern of hair keratin expression in the normal nail matrix is maintained in OM, to compare and contrast follicular tumors with matrix differentiation in OM, and to furnish morphological and immunohistochemical markers of the onychogenic capacity of OM.

Onychomatricoma: new clinical and histological features. A review of 19 tumors.

To further define the clinicopathological spectrum of onychomatricoma (OM). We report the clinical feature, histological, and immunophenotypic characteristics of 19 cases of OM diagnosed between 2002 and 2007. The characteristic histologic appearance of OM is sometimes difficult to grasp because of 3 main factors: the anatomic particularities of the nail apparatus, the often fragmented aspect of the tissue specimen, and the choice of the section planes, which strongly modified the morphologic appearances observed.

Surgical approach to fragility fractures: problems and perspectives.

The frequency of osteoporosis is constantly increasing all over the world. This pathology generates several problems, mostly due to fragility fractures, the worst consequence of impaired bone quality. Osteoporotic fractures often cause disability and loss of independence, partly because fracture fixation is not always easy and durable.

Incidence of fragility fractures.

Osteoporosis is an increasingly frequent pathology, especially due to the remarkable increase in the average age of the population. It is a skeletal disorder characterized by a reduction in bone strength which predisposes to increased fracture risk. It has been calculated that there are more than 200 million osteoporotic subjects in the world: one in three women and one in eight men over 50 years of age have osteoporosis.

Prevalence of stratified epithelium-specific antinuclear antibodies in 138 patients with lichen planus.

Background: Antibodies to stratified epithelia characterize chronic ulcerative stomatitis, an entity that very closely resembles erosive lichen planus both clinically and histologically. These antibodies are directed against a 70-kd antigen.

Objective: Our aim was to verify whether antibodies to stratified epithelia are present in patients with common lichen planus.

A comparative prospective study of dynamic variable angle hip screw and Gamma nail in intertrochanteric hip fractures.

Purpose: To compare the results between a variable angle dynamic screw-plate(DMS) and the Gamma nail in the treatment of intertrochanteric hip fractures.

Methods: A comparative prospective study of 142 patients (AO/OTA Type 31-A1; A2; A3 and B2) treated by variable angle dynamic screw-plate (DMS Group = 71) or by intramedullary nailing (Gamma Nail Group = 71).

Results: At the 12-month follow-up, we did not find any statistically significant difference, intraoperatively, radiographically, or clinically, between the two groups of patients, except for shortening.

Physeal fractures of the distal radius and ulna: long-term prognosis.

Objectives: The long-term prognosis of injuries to the distal physis of forearm bones, including complications such as radioulnar length discrepancy and styloid nonunion, has not been extensively studied. Reliable radiographic prognostic criteria to predict physeal disturbance at trauma are also lacking. The aim of this study is to investigate both issues.